Center for Interventional Endoscopy, Florida Hospital, Orlando, Florida, USA.
Dig Endosc. 2014 Jan;26 Suppl 1:62-9. doi: 10.1111/den.12146. Epub 2013 Aug 28.
Endoscopic ultrasound (EUS) is an indispensable tool for tissue acquisition in patients with gastrointestinal tumors. While fine-needle aspiration (FNA) has been routinely carried out for establishing tissue diagnosis, the emerging concept of tailoring chemotherapeutic agents based on molecular markers has increased the demand for core tissue procurement by means of EUS-guided fine-needle biopsy (EUS-FNB). In addition, FNB may offset the limitations of FNA wherein the diagnostic sensitivity is incumbent on the availability of an onsite cytopathologist. Given the increasing number of procedures being done, developing a unit-specific algorithmic approach for needle selection is important to improve the procedural efficiency and utilization of resources. Finally, the best outcomes can be attained only by practicing evidence-based techniques, procuring adequate quantity of sample for ancillary studies and processing the specimens appropriately.
内镜超声（EUS）是胃肠道肿瘤患者获取组织的不可或缺的工具。虽然细针抽吸（FNA）已常规用于建立组织诊断，但基于分子标志物定制化疗药物的新观念增加了对 EUS 引导下细针活检（EUS-FNB）获取核心组织的需求。此外，FNB 可能会弥补 FNA 的局限性，其中诊断灵敏度取决于现场细胞学专家的可用性。鉴于进行的手术数量不断增加，为针具选择开发特定于单位的算法方法对于提高程序效率和资源利用至关重要。最后，只有通过实践基于证据的技术、为辅助研究获取足够数量的样本并适当处理标本，才能获得最佳结果。
