Department of Cardiology, First Affiliated Hospital, Dalian Medical University, Dalian, Liaoning 116011, China.
Chin Med J (Engl). 2013;126(18):3481-5.
Females with acute myocardial infarction (AMI) have a higher risk of adverse outcomes because of receiving less evidence-based medical care. Our aim was to investigate the gender disparity in early death after ST-elevation myocardial infarction (STEMI) in the current era.
A total of 1429 consecutive patients with STEMI in the Liaoning district were analyzed. We compared hospital care and cardiac event data by sex for in-patients with acute STEMI within 24 hours of symptom onset.
In the emergency reperfusion group (n = 754), in-hospital mortality occurred in 4.2% of the males and 11.2% of the females (P = 0.001). In the non-emergency reperfusion group (n = 675), in-hospital mortality occurred in 13.0% of the males and 22.9% of the females (P = 0.001). Multivariate Logistic regression analysis revealed female sex as an independent risk factor of death for STEMI patients during hospitalization (OR = 1.691, P = 0.007). After controlling for patients who died within 24 hr after admission, female sex was no longer an independent risk factor (OR = 1.409, P = 0.259).
Female sex was an independent risk factor for in-hospital mortality of STEMI patients, which is explained by an excess of very early deaths.
由于接受的循证医学护理较少，女性急性心肌梗死（AMI）患者的不良预后风险更高。我们的目的是调查在当前时代女性 ST 段抬高型心肌梗死（STEMI）患者早期死亡的性别差异。
分析了辽宁地区 1429 例连续 STEMI 患者。我们比较了发病 24 小时内急性 STEMI 住院患者的性别间医院治疗和心脏事件数据。
在急诊再灌注组（n = 754）中，男性住院死亡率为 4.2%，女性为 11.2%（P = 0.001）。在非急诊再灌注组（n = 675）中，男性住院死亡率为 13.0%，女性为 22.9%（P = 0.001）。多变量 Logistic 回归分析显示，女性是 STEMI 患者住院期间死亡的独立危险因素（OR = 1.691，P = 0.007）。在控制了入院 24 小时内死亡的患者后，女性不再是独立的危险因素（OR = 1.409，P = 0.259）。
女性是 STEMI 患者住院期间死亡率的独立危险因素，这可以解释为早期死亡人数过多。
