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[内科深静脉血栓形成的危险因素:318例回顾性研究]

[Risk factor for deep venous thrombosis in internal medicine: A retrospective study of 318 cases].

作者信息

Ben Salah R, Frikha F, Kaddour N, Saidi N, Snoussi M, Marzouk S, Jallouli M, Frigui M, Bahloul Z

机构信息

Service de médecine interne, CHU Hédi Chaker, 3029 Sfax, Tunisie.

Service de médecine interne, CHU Hédi Chaker, 3029 Sfax, Tunisie.

出版信息

Ann Cardiol Angeiol (Paris). 2014 Feb;63(1):11-6. doi: 10.1016/j.ancard.2013.06.005. Epub 2013 Jul 16.

DOI:10.1016/j.ancard.2013.06.005
PMID:24035260
Abstract

OBJECTIVE

Venous thromboembolic disease is a common condition. Deep vein thrombosis (DVT) and pulmonary embolism are the most common manifestation but other locations may also occur. The objectives of the study were to estimate the incidence and determine the epidemiologic, topographic and associated conditions of venous thromboembolic disease in a department of internal medicine.

METHODS

A retrospective study of a series of 318 cases of DVT was conducted in Internal Medicine CHU Hedi Chaker, Sfax, during a period of 15 years (1996-2010).

RESULTS

DVT of the lower limbs was the most common location (87%). Other sites of DVT was noted in 16.35% of cases including upper limbs (19 cases), vena cava (16 cases), cerebral veins (10 cases), portal vein (10 cases) and hepatic vein (3 cases). A risk factor of VTE was found in 274 patients (86.1%). A state of thrombophilia was retained in 203 patients (63.5%). It was a hereditary thrombophilia (22.6%), an antiphospholipids syndrome (19.1%), Behçet's disease (16.4%) and neoplasia (7.2%). The study of the distribution of venous thrombosis as the seat and etiology showed that: the antiphospholipid syndrome was the most associated conditions with the upper extremity DVT (31.7%) whereas Behçet's disease was the most frequent etiology of vena cava thrombosis (7 cases) and the cerebral vein thrombosis especially in young males.

摘要

目的

静脉血栓栓塞性疾病是一种常见病症。深静脉血栓形成(DVT)和肺栓塞是最常见的表现形式,但也可能发生在其他部位。本研究的目的是估计内科某科室静脉血栓栓塞性疾病的发病率,并确定其流行病学、部位及相关情况。

方法

对突尼斯斯法克斯市赫迪·查克医院内科15年期间(1996 - 2010年)的318例深静脉血栓形成病例进行回顾性研究。

结果

下肢深静脉血栓形成是最常见的部位(87%)。在16.35%的病例中发现了其他深静脉血栓形成部位,包括上肢(19例)、腔静脉(16例)、脑静脉(10例)、门静脉(10例)和肝静脉(3例)。274例患者(86.1%)存在静脉血栓栓塞的危险因素。203例患者(63.5%)存在血栓形成倾向。其中遗传性血栓形成倾向占22.6%,抗磷脂综合征占19.1%,白塞病占16.4%,肿瘤占7.2%。对静脉血栓形成的部位和病因分布研究表明:抗磷脂综合征与上肢深静脉血栓形成的相关性最高(31.7%),而白塞病是腔静脉血栓形成(7例)尤其是脑静脉血栓形成最常见的病因,特别是在年轻男性中。

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