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微创二尖瓣手术:主动脉夹闭技术对早期结果的影响。

Minimally invasive mitral valve surgery: influence of aortic clamping technique on early outcomes.

机构信息

Department of Surgery, Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada.

出版信息

Ann Thorac Surg. 2013 Dec;96(6):2116-22. doi: 10.1016/j.athoracsur.2013.07.015. Epub 2013 Sep 12.

DOI:10.1016/j.athoracsur.2013.07.015
PMID:24035304
Abstract

BACKGROUND

Several methods of aortic clamping have been described for minimally invasive mitral valve surgery (MIMVS). The aim of this study was to compare the endoaortic balloon occlusion technique with the transthoracic clamp approach in terms of perioperative outcomes.

METHODS

Between May 2006 and October 2011, a total of 259 patients underwent MIMVS through a 4 to 5 cm right anterolateral minithoracotomy. In 243 (93.8%) of these, the aorta was clamped using either the endoaortic balloon occlusion technique (endoballoon, n = 140) or the transthoracic clamp technique (transthoracic, n = 103).

RESULTS

Patients in the endoballoon group had significantly longer operating time (4.3 ± 1.0 hours vs 3.2 ± 0.8 hours, p < 0.001), cardiopulmonary bypass time (143 ± 44 minutes vs 111 ± 29 minutes , p < 0.001), and cross-clamp time (114 ± 38 minutes vs 86 ± 23 minutes , p < 0.001). Perioperative blood loss was higher in the endoballoon group (287 ± 239 mL vs 213 ± 189 mL, p = 0.008) as was the mean postoperative creatinine kinase-MB level (36 ± 44 μg/L vs 26 ± 12 μg/L, p = 0.011). The repair rate was 99% or greater in both groups (p = 0.99). All patients left the operating room with no or trivial residual mitral regurgitation on transesophageal echocardiographic evaluation. In the endoballoon group there was 1 stroke (1%) and 5 myocardial infarctions (4%), compared with 2 strokes (2%) in the transthoracic group (p = not significant). There were 4 cases of postoperative cardiogenic shock, all of which occurred in the endoballoon group (p = 0.14). In-hospital mortality occurred in 2 patients from each group (p = 0.99).

CONCLUSIONS

Minimally invasive mitral valve surgery can be performed successfully using either the endoaortic balloon technique or the transthoracic clamp approach. However, the transthoracic technique results in shorter operation time, less perioperative bleeding and better myocardial protection.

摘要

背景

微创二尖瓣手术(MIMVS)有多种主动脉夹闭方法。本研究旨在比较腔内球囊阻断技术与经胸钳夹技术在围手术期结果方面的差异。

方法

2006 年 5 月至 2011 年 10 月,共有 259 例患者通过 4-5cm 的右前外侧小开胸手术接受 MIMVS。其中 243 例(93.8%)采用腔内球囊阻断技术(腔内球囊,n=140)或经胸钳夹技术(经胸,n=103)进行主动脉夹闭。

结果

腔内球囊组的手术时间(4.3±1.0 小时 vs 3.2±0.8 小时,p<0.001)、体外循环时间(143±44 分钟 vs 111±29 分钟,p<0.001)和阻断时间(114±38 分钟 vs 86±23 分钟,p<0.001)均显著更长。腔内球囊组围手术期出血量(287±239 毫升 vs 213±189 毫升,p=0.008)和平均术后肌酸激酶-MB 水平(36±44 微克/升 vs 26±12 微克/升,p=0.011)均较高。两组修复率均在 99%或以上(p=0.99)。所有患者在经食管超声心动图评估下均无或仅有轻微的残余二尖瓣反流离开手术室。腔内球囊组发生 1 例(1%)脑卒中,5 例(4%)心肌梗死,而经胸组发生 2 例(2%)脑卒中(p=无显著差异)。有 4 例术后心源性休克,均发生在腔内球囊组(p=0.14)。两组各有 2 例院内死亡(p=0.99)。

结论

微创二尖瓣手术可成功采用腔内球囊技术或经胸钳夹技术进行。然而,经胸技术可缩短手术时间,减少围手术期出血,更好地保护心肌。

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