Kaysen Debra, Schumm Jeremiah, Pedersen Eric R, Seim Richard W, Bedard-Gilligan Michele, Chard Kathleen
Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA, United States; Department of Psychology, University of Washington, Seattle, WA, United States.
Addict Behav. 2014 Feb;39(2):420-7. doi: 10.1016/j.addbeh.2013.08.016. Epub 2013 Aug 24.
Posttraumatic stress disorder (PTSD) and alcohol-use disorders (AUD) frequently present comorbidity in veteran populations. Traditionally those with alcohol dependence have been excluded from PTSD treatment outcome studies, thus we do not know how those with alcohol dependence may tolerate or respond to PTSD-specific interventions; no studies to date have examined the extent to which cognitive PTSD interventions are tolerated or effective for those with comorbid PTSD/AUD. The present study examines the extent to which CPT is tolerated by and effective in treating PTSD symptoms for veterans with PTSD and AUD, as compared to veterans with PTSD only in an outpatient treatment setting. Data were obtained through chart review of 536 veterans diagnosed with PTSD who had received at least 1 session of CPT at a Midwestern US Veterans Affairs hospital. Nearly half (n=264, 49.3%) of the veterans in the study exhibited a current or past AUD diagnosis. Participants were grouped into the following diagnostic groups: current AUD (past 12 months), past AUD (prior to 12 months), and no AUD. Participants completed an average of 9 sessions of CPT with no significant difference between AUD diagnostic groups on the number of CPT sessions completed. Individuals with past AUD had higher initial symptoms of self-reported PTSD symptoms than those with no AUD. All groups reported significant reductions in PTSD symptoms and depression over time. Overall, the results suggest that CPT appears well tolerated among veterans with comorbid AUD and is associated with significant reductions in symptoms of PTSD and depression in an outpatient treatment setting.
创伤后应激障碍(PTSD)和酒精使用障碍(AUD)在退伍军人中经常合并出现。传统上,酒精依赖者被排除在PTSD治疗结果研究之外,因此我们不知道酒精依赖者对PTSD特异性干预措施的耐受性或反应如何;迄今为止,尚无研究探讨认知PTSD干预措施对合并PTSD/AUD者的耐受性或有效性。本研究考察了与仅患有PTSD的退伍军人相比,认知处理疗法(CPT)在门诊治疗环境中对患有PTSD和AUD的退伍军人的耐受性以及治疗PTSD症状的有效性。数据通过对美国中西部一家退伍军人事务医院536名被诊断为PTSD且至少接受过1次CPT治疗的退伍军人的病历审查获得。研究中近一半(n = 264,49.3%)的退伍军人目前或过去被诊断为AUD。参与者被分为以下诊断组:目前患有AUD(过去12个月内)、过去患有AUD(12个月之前)和无AUD。参与者平均完成了9次CPT治疗,AUD诊断组之间完成的CPT治疗次数无显著差异。过去患有AUD的个体自我报告的PTSD症状初始症状比无AUD的个体更高。随着时间的推移,所有组报告的PTSD症状和抑郁症状均显著减轻。总体而言,结果表明CPT在合并AUD的退伍军人中耐受性良好,并且在门诊治疗环境中与PTSD和抑郁症状的显著减轻相关。