Guinet M, Michel C
Université de Bourgogne, Campus Universitaire, UFR STAPS, BP 27877, Dijon F-21078, France; INSERM, U 1093, Cognition, Action et Plasticité sensorimotrice, Dijon F-21078, France.
Neuroscience. 2013 Dec 19;254:443-51. doi: 10.1016/j.neuroscience.2013.08.067. Epub 2013 Sep 13.
Studies involving therapeutic combinations reveal an important benefit in the rehabilitation of neglect patients when compared to single therapies. In light of these observations our present work examines, in healthy individuals, sensorimotor and cognitive after-effects of prism adaptation and neck muscle vibration applied individually or simultaneously. We explored sensorimotor after-effects on visuo-manual open-loop pointing, visual and proprioceptive straight-ahead estimations. We assessed cognitive after-effects on the line bisection task. Fifty-four healthy participants were divided into six groups designated according to the exposure procedure used with each: 'Prism' (P) group; 'Vibration with a sensation of body rotation' (Vb) group; 'Vibration with a move illusion of the LED' (Vl) group; 'Association with a sensation of body rotation' (Ab) group; 'Association with a move illusion of the LED' (Al) group; and 'Control' (C) group. The main findings showed that prism adaptation applied alone or combined with vibration showed significant adaptation in visuo-manual open-loop pointing, visual straight-ahead and proprioceptive straight-ahead. Vibration alone produced significant after-effects on proprioceptive straight-ahead estimation in the Vl group. Furthermore all groups (except C group) showed a rightward neglect-like bias in line bisection following the training procedure. This is the first demonstration of cognitive after-effects following neck muscle vibration in healthy individuals. The simultaneous application of both methods did not produce significant greater after-effects than prism adaptation alone in both sensorimotor and cognitive tasks. These results are discussed in terms of transfer of sensorimotor plasticity to spatial cognition in healthy individuals.
与单一疗法相比，涉及治疗组合的研究显示出在忽视症患者康复方面的重要益处。鉴于这些观察结果，我们目前的工作在健康个体中研究了单独或同时应用棱镜适应和颈部肌肉振动后的感觉运动和认知后效应。我们探索了感觉运动后效应对视手动开环指向、视觉和本体感觉的前方估计的影响。我们评估了认知后效应在线段二等分任务中的表现。54名健康参与者被分为六组，根据每组使用的暴露程序命名：“棱镜”（P）组；“伴有身体旋转感觉的振动”（Vb）组；“伴有LED移动错觉的振动”（Vl）组；“伴有身体旋转感觉的联合”（Ab）组；“伴有LED移动错觉的联合”（Al）组；以及“对照组”（C）组。主要研究结果表明，单独应用或与振动联合应用的棱镜适应在视手动开环指向、视觉前方和本体感觉前方方面显示出显著的适应性。单独的振动在Vl组的本体感觉前方估计中产生了显著的后效应。此外，所有组（除C组外）在训练程序后的线段二等分中均表现出向右的类似忽视的偏差。这是首次在健康个体中证明颈部肌肉振动后的认知后效应。在感觉运动和认知任务中，两种方法同时应用并没有比单独应用棱镜适应产生显著更大的后效应。我们从健康个体中感觉运动可塑性向空间认知的转移角度讨论了这些结果。
