School of Health and Social Care, University of Greenwich, London, United Kingdom.
Department of Clinical Neuropsychology, VU University Amsterdam, Amsterdam, The Netherlands.
Arch Phys Med Rehabil. 2014 Jan;95(1):175-187.e9. doi: 10.1016/j.apmr.2013.08.241. Epub 2013 Sep 10.
To conduct a systematic review and meta-analysis to establish the association between pain and falls in community-dwelling older adults.
Electronic databases from inception until March 1, 2013, including Cochrane Library, CINAHL, EBSCO, EMBASE, PubMed, and PsycINFO.
Two reviewers independently conducted the searches and completed methodological assessment of all included studies. Studies were included that (1) focused on adults older than 60 years; (2) recorded falls over 6 or more months; and (3) identified a group with and without pain. Studies were excluded that included (1) participants with dementia or a neurologic condition (eg, stroke); (2) participants whose pain was caused by a previous fall; or (3) individuals with surgery/fractures in the past 6 months.
One author extracted all data, and this was independently validated by another author.
A total of 1334 articles were screened, and 21 studies met the eligibility criteria. Over 12 months, 50.5% of older adults with pain reported 1 or more falls compared with 25.7% of controls (P<.001). A global meta-analysis with 14 studies (n=17,926) demonstrated that pain was associated with an increased odds of falling (odds ratio [OR]=1.56; 95% confidence interval [CI], 1.36-1.79; I(2)=53%). A subgroup meta-analysis incorporating studies that monitored falls prospectively established that the odds of falling were significantly higher in those with pain (n=4674; OR=1.71; 95% CI, 1.48-1.98; I(2)=0%). Foot pain was strongly associated with falls (n=691; OR=2.38; 95% CI, 1.62-3.48; I(2)=8%) as was chronic pain (n= 5367; OR=1.80; 95% CI, 1.56-2.09; I(2)=0%).
Community-dwelling older adults with pain were more likely to have fallen in the past 12 months and to fall again in the future. Foot and chronic pain were particularly strong risk factors for falls, and clinicians should routinely inquire about these when completing falls risk assessments.
系统回顾和荟萃分析,以确定社区居住的老年人中疼痛与跌倒之间的关系。
电子数据库从成立到 2013 年 3 月 1 日,包括 Cochrane 图书馆、CINAHL、EBSCO、EMBASE、PubMed 和 PsycINFO。
两名审查员独立进行检索并对所有纳入研究进行方法学评估。纳入的研究包括:(1) 年龄大于 60 岁的成年人;(2) 记录 6 个月以上的跌倒;(3) 确定有疼痛和无疼痛的组。排除的研究包括:(1) 痴呆或神经疾病(如中风)患者;(2) 疼痛由先前跌倒引起的患者;或(3) 过去 6 个月内接受手术/骨折的患者。
一名作者提取所有数据,另一名作者独立验证。
共筛选了 1334 篇文章,有 21 篇符合入选标准。在 12 个月内,有疼痛的老年人中有 50.5%报告发生了 1 次或多次跌倒,而对照组为 25.7%(P<.001)。对 14 项研究(n=17926)进行的全球荟萃分析表明,疼痛与跌倒的几率增加相关(比值比[OR]=1.56;95%置信区间[CI],1.36-1.79;I(2)=53%)。纳入前瞻性监测跌倒的研究的亚组荟萃分析表明,疼痛患者跌倒的几率显著更高(n=4674;OR=1.71;95%CI,1.48-1.98;I(2)=0%)。足部疼痛与跌倒强烈相关(n=691;OR=2.38;95%CI,1.62-3.48;I(2)=8%),慢性疼痛也与跌倒密切相关(n=5367;OR=1.80;95%CI,1.56-2.09;I(2)=0%)。
社区居住的有疼痛的老年人在过去 12 个月中更有可能跌倒,并且将来再次跌倒的可能性更大。足部疼痛和慢性疼痛是跌倒的特别强烈的危险因素,临床医生在进行跌倒风险评估时应常规询问这些情况。