Silva Jaqueline Raymondi, Medeiros Larissa Campos de, Reis Vinicius Pinho dos, Chavez Juliana Helena, Munhoz Thiago Demarchi, Borges Gustavo Puia, Soares Otavio Augusto Brioschi, Campos Carlos Henrique Coelho de, Machado Rosangela Zacarias, Baldani Cristiane Divan, Silva Maria Luana Cristiny Rodrigues, Faria Joice Lara Maia, Silva Edson Elias da, Figueiredo Luiz Tadeu Moraes
Mem Inst Oswaldo Cruz. 2013 Nov;108(7):921-3. doi: 10.1590/S0074-02762013005000001.
Since the emergence of West Nile virus (WNV) in North America in 1999, there have been several reports of WNV activity in Central and South American countries. To detect WNV in Brazil, we performed a serological survey of horses from different regions of Brazil using recombinant peptides from domain III of WNV. Positive samples were validated with the neutralisation test. Our results showed that of 79 ELISA-positive horses, nine expressed WNV-specific neutralising antibodies. Eight of the infected horses were from the state of Mato Grosso do Sul and one was from the state of Paraíba. Our results provide additional evidence for the emergence of WNV in Brazil and for its circulation in multiple regions of the country.
自1999年西尼罗河病毒（WNV）在北美出现以来，已有多份关于该病毒在中美洲和南美洲国家活动的报告。为了在巴西检测西尼罗河病毒，我们使用来自西尼罗河病毒结构域III的重组肽对巴西不同地区的马匹进行了血清学调查。阳性样本通过中和试验进行验证。我们的结果显示，在79份ELISA检测呈阳性的马匹中，有9份表达了西尼罗河病毒特异性中和抗体。其中8匹受感染的马来自南马托格罗索州，1匹来自帕拉伊巴州。我们的结果为西尼罗河病毒在巴西的出现及其在该国多个地区的传播提供了更多证据。
