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本文引用的文献

1
Generation of retinal cells from pluripotent stem cells.诱导多能干细胞分化为视网膜细胞。
Prog Brain Res. 2012;201:171-81. doi: 10.1016/B978-0-444-59544-7.00008-1.
2
iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration.Best 病的 iPS 细胞建模：遗传性黄斑变性发病机制的新见解。
Hum Mol Genet. 2013 Feb 1;22(3):593-607. doi: 10.1093/hmg/dds469. Epub 2012 Nov 8.
3
Self-formation of optic cups and storable stratified neural retina from human ESCs.人胚胎干细胞诱导形成的自组织类脑器官。
Cell Stem Cell. 2012 Jun 14;10(6):771-785. doi: 10.1016/j.stem.2012.05.009.
4
Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins.在确定的条件下使用纯化的细胞外基质蛋白将人多能干细胞分化为视网膜色素上皮细胞。
J Tissue Eng Regen Med. 2013 Aug;7(8):642-53. doi: 10.1002/term.1458. Epub 2012 Apr 18.
5
Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses.血液来源的人类诱导多能干细胞生成具有形成视网膜层和发育突触能力的类视囊结构。
Invest Ophthalmol Vis Sci. 2012 Apr 18;53(4):2007-19. doi: 10.1167/iovs.11-9313.
6
Guiding the morphogenesis of dissociated newborn mouse retinal cells and hES cell-derived retinal cells by soft lithography-patterned microchannel PLGA scaffolds.通过软光刻图案化微通道聚乳酸-羟基乙酸共聚物支架引导分离新生鼠视网膜细胞和人胚胎干细胞源性视网膜细胞的形态发生。
Biomaterials. 2012 Feb;33(5):1396-405. doi: 10.1016/j.biomaterials.2011.10.083. Epub 2011 Nov 23.
7
Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa.外显子组测序和诱导多能干细胞分析鉴定出纤毛相关基因精子发生相关激酶（MAK）是导致色素性视网膜炎的原因。
Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):E569-76. doi: 10.1073/pnas.1108918108. Epub 2011 Aug 8.
8
Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment.人多能干细胞诱导形成的类视囊泡结构有助于实现视网膜疾病治疗的个体化策略。
Stem Cells. 2011 Aug;29(8):1206-18. doi: 10.1002/stem.674.
9
Human induced pluripotent stem-derived retinal pigment epithelium (RPE) cells exhibit ion transport, membrane potential, polarized vascular endothelial growth factor secretion, and gene expression pattern similar to native RPE.人诱导多能干细胞衍生的视网膜色素上皮 (RPE) 细胞表现出类似天然 RPE 的离子转运、膜电位、极化血管内皮生长因子分泌和基因表达模式。
Stem Cells. 2011 May;29(5):825-35. doi: 10.1002/stem.635.
10
Self-organizing optic-cup morphogenesis in three-dimensional culture.三维培养中的自组织视杯形态发生。
Nature. 2011 Apr 7;472(7341):51-6. doi: 10.1038/nature09941.

Modeling retinal degenerative diseases with human iPS-derived cells: current status and future implications.

作者信息

Gamm David M, Phillips M Joseph, Singh Ruchira

机构信息

Department of Ophthalmology and Visual Sciences, McPherson Eye Research Institute, Waisman Center Stem Cell Research Program, University of Wisconsin School of Medicine and Public Health, Waisman Center, Room T609, 1500 Highland Ave, Madison, WI 53705, USA.

出版信息

Expert Rev Ophthalmol. 2013 Jun 1;8(3):213-216. doi: 10.1586/eop.13.14.

DOI:10.1586/eop.13.14
PMID:24039627
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3770479/
Abstract
摘要