Cardiovascular Research Centre, Australian Catholic University, Melbourne, Victoria, Australia.
PLoS One. 2013 Sep 5;8(9):e73459. doi: 10.1371/journal.pone.0073459. eCollection 2013.
Despite evidence that patients with coronary heart disease (CHD) and their partners report significant psychological distress, and suggestions that involving partners in interventions alleviates such distress, no systematic reviews have examined this. The objective of this study was to systematically review evidence on the effectiveness of psychological interventions for patients with CHD and their partners.
CENTRAL, Medline, EMBASE, CINAHL and PsycINFO databases were searched through October 2012. Randomized controlled trials evaluating psychological interventions for patients with CHD and their partners were included. Selection of studies, study appraisal, data extraction and analysis were undertaken using standard methods.
Seven studies comprising 673 participants were included, two of which indicated that psychological interventions result in modest improvements in patients' depressive symptoms, anxiety, knowledge of disease and treatment, and satisfaction with care, and in partners' anxiety, knowledge and satisfaction. In partners, there was a non-significant trend for improvements in depressive symptoms. One study showed a beneficial effect on blood pressure. There was no evidence of a significant effect on mortality, morbidity or cardiovascular risk factors for patients or social support for patients and partner.
The small number of studies included in the review had generally poor methodology, as shown by the risk of bias, and were performed over 10 years ago. As only two of the seven studies resulted in modest improvements in outcomes, no firm conclusions can be drawn as to the effectiveness of such interventions in this population.
尽管有证据表明冠心病 (CHD) 患者及其伴侣报告存在明显的心理困扰,并且有研究表明让伴侣参与干预可以减轻这种困扰,但目前还没有系统地评估过这一点。本研究的目的是系统地评估针对 CHD 患者及其伴侣的心理干预措施的有效性。
通过 CENTRAL、Medline、EMBASE、CINAHL 和 PsycINFO 数据库对截至 2012 年 10 月的文献进行了检索。纳入了评估针对 CHD 患者及其伴侣的心理干预措施的随机对照试验。采用标准方法进行研究选择、研究评估、数据提取和分析。
纳入了 7 项研究,共 673 名参与者,其中两项研究表明,心理干预措施可使患者的抑郁症状、焦虑症状、疾病和治疗知识、以及对护理的满意度得到适度改善,使伴侣的焦虑症状、知识水平和满意度得到适度改善。在伴侣中,抑郁症状有改善的趋势,但无统计学意义。一项研究显示,心理干预对血压有有益影响。但对患者的死亡率、发病率或心血管危险因素,或对患者和伴侣的社会支持,均无显著影响。
本综述纳入的研究数量较少,方法学通常较差,存在偏倚风险,且均是在 10 年前开展的。由于仅有两项研究显示出对结局有适度的改善,因此无法确定这种干预措施在这一人群中的有效性。