Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil(1).
Psychiatry Res. 2013 Dec 30;210(3):906-12. doi: 10.1016/j.psychres.2013.08.036. Epub 2013 Sep 13.
The goals of the present study were to determine the prevalence of depression in the adult population of Sao Paulo, Brazil and to explore the relationship among sociodemographic, physical and psychological factors, sleep-related symptoms and polysomnography parameters. Participants of a cross-sectional study (N = 1101) were administered questionnaires and submitted to polysomnography. A score > 20 in the Beck Depression Inventory was used to describe depression. Results revealed that the prevalence of depression was 10.9%. Estimates were higher in women and were significantly higher among housewives, non-workers and individuals with lower education and income. A combination of sleep-related symptoms and impaired quality of life was 2.5 times more frequent among depressed than non-depressed. Co-morbid insomnia and anxiety were positively associated to depressive symptomatology. There were no alterations in the polysomnography parameters, in either group. The occurrence of sleep apnea with values on the apnea-hypopnea index ≥ 5 was similar and frequent in both groups (around 30%). The findings suggest that depressive symptoms were associated with low education, low income, severe comorbid symptomatology, and impaired quality of life. Considering the high prevalence of sleep apnea, these results point to potential social and financial burdens associated with the depressive symptomatology and various sleep diagnoses.
本研究的目的是确定巴西圣保罗市成年人群中抑郁症的患病率,并探讨社会人口学、身体和心理因素、与睡眠相关的症状和多导睡眠图参数之间的关系。一项横断面研究(N=1101)的参与者接受了问卷调查并接受了多导睡眠图检查。贝克抑郁量表(Beck Depression Inventory)得分>20 用于描述抑郁。结果显示,抑郁症的患病率为 10.9%。女性的患病率较高,家庭主妇、非劳动者以及受教育程度和收入较低的个体的患病率明显较高。与非抑郁组相比,存在睡眠相关症状和生活质量受损的患者中,抑郁的发生率高 2.5 倍。合并的失眠和焦虑与抑郁症状显著相关。两组的多导睡眠图参数均无改变。两组的睡眠呼吸暂停发生率相似且均较高(约 30%),呼吸暂停低通气指数(apnea-hypopnea index)值≥5。这些发现表明,抑郁症状与低教育程度、低收入、严重合并症状和生活质量受损有关。考虑到睡眠呼吸暂停的高患病率,这些结果表明与抑郁症状和各种睡眠诊断相关的潜在社会和经济负担。