Armon C, Daube J R, Windebank A J, Kurland L T
Department of Neurology, Mayo Clinic, Rochester, MN 55905.
Neurology. 1990 Jan;40(1):172-4. doi: 10.1212/wnl.40.1.172.
There is a paucity of reports of classic amyotrophic lateral sclerosis (ALS) developing in survivors of paralytic poliomyelitis. We describe a patient with classic ALS and an antecedent paralytic disease thought to have been poliomyelitis from which she recovered completely. If the paucity of ALS preceded by true poliomyelitis is not merely a matter of underreporting, antecedent paralytic poliomyelitis may have a protective role against the development of ALS. This has implications relevant to pathogenesis and to projected secular trends of ALS incidence since the introduction of poliomyelitis vaccines. There is a need to establish the incidence of cases of classic ALS in patients with antecedent poliomyelitis.
关于麻痹性脊髓灰质炎幸存者发生经典型肌萎缩侧索硬化（ALS）的报道较少。我们描述了一名患有经典型ALS的患者，其先前患有被认为是脊髓灰质炎的麻痹性疾病，且已完全康复。如果真正的脊髓灰质炎之后发生ALS的情况较少不仅仅是报告不足的问题，那么先前的麻痹性脊髓灰质炎可能对ALS的发生具有保护作用。这对于发病机制以及自脊髓灰质炎疫苗引入以来ALS发病率的预计长期趋势具有重要意义。有必要确定先前患有脊髓灰质炎的患者中经典型ALS病例的发病率。
