运动神经元病与既往脊髓灰质炎。日本最北部岛屿北海道的地理研究。肌萎缩侧索硬化症研究组。

Motor neuron disease and past poliomyelitis. Geographic study in Hokkaido, the northern-most island of Japan. ALS Study Group.

作者信息

Moriwaka F, Okumura H, Tashiro K, Hamada T, Matsumoto A, Matsumoto H, Itoh N, Shindo R, Takahata N

机构信息

Department of Neurology, Hokkaido University School of Medicine, Sapporo, Japan.

出版信息

J Neurol. 1993 Jan;240(1):13-6. doi: 10.1007/BF00838439.

DOI:10.1007/BF00838439

PMID:8423458

Abstract

We carried out a survey on the cases of motor neuron disease (MND) occurring in Hokkaido between 1980 and 1989 in order to establish whether there is a relationship between MND and poliomyelitis. Hokkaido, the northern-most island of Japan, was one of the most affected areas during the poliomyelitis epidemic of the late 1940s to 1950s. We ascertained 389 cases of MND for these 10 years and 2,171 cases of paralytic poliomyelitis for the period 1949-1958, and analysed their geographic distributions. No significant correlation was found between MND and poliomyelitis in their geographic distributions.

摘要

我们对1980年至1989年期间在北海道发生的运动神经元病（MND）病例进行了一项调查，以确定MND与小儿麻痹症之间是否存在关联。北海道是日本最北部的岛屿，在20世纪40年代末至50年代的小儿麻痹症流行期间是受影响最严重的地区之一。我们确定了这10年中的389例MND病例以及1949年至1958年期间的2171例麻痹性小儿麻痹症病例，并分析了它们的地理分布。在地理分布上，未发现MND与小儿麻痹症之间存在显著相关性。