Kidd D, Williams A J, Howard R S
Department of Neurology, St Thomas' Hospital, London, UK.
Postgrad Med J. 1996 Nov;72(853):641-7. doi: 10.1136/pgmj.72.853.641.
1996 is polio awareness year. This paper reviews the clinical syndrome of acute paralytic poliomyelitis and its sequelae. We discuss epidemiological studies of the syndrome of late functional deterioration many years after the acute infection and the current hypotheses of the pathophysiology of such disorders. Recent evidence has suggested that potentially treatable factors may be implicated in the majority of such patients and it is therefore important to exclude such disorders before attributing late functional deterioration to progressive post-polio muscular atrophy.
1996年是小儿麻痹症宣传年。本文回顾了急性麻痹性脊髓灰质炎的临床综合征及其后遗症。我们讨论了急性感染多年后迟发性功能衰退综合征的流行病学研究以及此类疾病病理生理学的当前假说。最近的证据表明,大多数此类患者可能涉及潜在可治疗的因素,因此在将迟发性功能衰退归因于小儿麻痹后遗症进行性肌肉萎缩之前,排除此类疾病很重要。