Montgomerie J Z, Gilmore D S, Canawati H N, Morrow J W
Department of Urology/Surgery, University of Southern California School of Medicine, Los Angeles.
Urology. 1990 Jan;35(1):93-5. doi: 10.1016/0090-4295(90)80024-h.
Ceftazidime was compared with moxalactam in the treatment of urinary tract infections in patients with spinal cord injury. Patients received ceftazidime or moxalactam, 500 mg twice daily for five days. Urine specimens were collected by urethral catheter. Adequate follow-up was obtained in 26 patients treated with ceftazidime and 13 patients treated with moxalactam. The infecting bacteria were not cultured in significant numbers from the urine of any patients after two to four days of antibiotics, except for 1 patient who had Pseudomonas aeruginosa persisting in the urine while receiving ceftazidime. At five to nine days after completing antibiotic therapy, the cure rate was 42 percent for ceftazidime and 15 percent for moxalactam. The rate of reinfection was significantly lower in the ceftazidime group than the moxalactam group.
在脊髓损伤患者的尿路感染治疗中，对头孢他啶和拉氧头孢进行了比较。患者接受头孢他啶或拉氧头孢治疗，每日两次，每次500毫克，共五天。通过尿道导管收集尿液标本。26例接受头孢他啶治疗的患者和13例接受拉氧头孢治疗的患者获得了充分的随访。除1例在接受头孢他啶治疗时尿液中持续存在铜绿假单胞菌的患者外，在使用抗生素两到四天后，任何患者的尿液中均未培养出大量感染细菌。在完成抗生素治疗后的五到九天，头孢他啶的治愈率为42%，拉氧头孢的治愈率为15%。头孢他啶组的再感染率明显低于拉氧头孢组。
