Acun Hediye, Zubaroglu Ali, Kemikler Gönül, Bozkurt Ahmet
Department of Biophysics, Faculty of Medicine, Harran University, Osmanbey Campus, Sanliurfa 63300, Turkey.
Radiat Prot Dosimetry. 2014;158(3):299-306. doi: 10.1093/rpd/nct225. Epub 2013 Sep 15.
This study presents a comparison of peripheral doses (PDs) measured using an ionisation chamber with treatment planning system (TPS) data and a Monte Carlo (MC) simulation of a 6-MV photon beam. The ion chamber measurements and MC simulation produced similar results for all out-of-field distances and field sizes considered in this study. For the 0° and 90° collimation angles, the average local per cent dose differences between the MC and TPS calculations were 2.7 % (range: -2.4, +22.6) and -1.7 % (range: -12.2, +10.8), respectively. The corresponding differences between the MC calculations and the ion chamber measurements were 2.2 % (range: -2.4, 24.7) and -1.8 % (range: -17, 15.2) for all field sizes and depths, respectively. Whereas the PDs increased with field sizes, the variations with depth were negligible at large distances. The TPS calculations usually yielded higher PDs than ion chamber measurements at distances close to the field edge. In contrast, at the farther distances, the TPS results indicated lower doses than both the ion chamber and the MC data. TPS data are not sufficient for use in calculating the out-of-field doses. These results can be used to estimate non-target organ doses to patients.
本研究比较了使用电离室测量的外周剂量(PDs)与治疗计划系统(TPS)数据以及6兆伏光子束的蒙特卡罗(MC)模拟结果。对于本研究中考虑的所有野外距离和射野大小,电离室测量和MC模拟产生了相似的结果。对于0°和90°准直角度,MC与TPS计算之间的平均局部剂量百分比差异分别为2.7%(范围:-2.4,+22.6)和-1.7%(范围:-12.2,+10.8)。对于所有射野大小和深度,MC计算与电离室测量之间的相应差异分别为2.2%(范围:-2.4,24.7)和-1.8%(范围:-17,15.2)。虽然PDs随射野大小增加,但在大距离处,其随深度的变化可忽略不计。在靠近射野边缘的距离处,TPS计算通常产生比电离室测量更高的PDs。相反,在更远的距离处,TPS结果显示的剂量低于电离室和MC数据。TPS数据不足以用于计算野外剂量。这些结果可用于估计患者非靶器官的剂量。