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脊索样脑膜瘤,多发性颅内脑膜瘤的一部分:病例报告及文献复习

Chordoid meningioma, part of a multiple intracranial meningioma: a case report & review.

作者信息

Sriram Prabu Rau

机构信息

Department of Neurosurgery, Queen Elizabeth Hospital 2, Lorong Bersatu, Off Jalan Damai, 88300 Luyang, Kota Kinabalu, Sabah, Malaysia.

出版信息

Malays J Med Sci. 2013 Jul;20(4):91-4.

Abstract

Chordoid meningioma, classified as atypical meningioma according to the World Health Organisation (WHO) classification, is a rare subtype, which represents only 0.5% of all meningiomas and is associated with a high incidence of recurrence. Multiple intracranial meningiomas are rare in non-neurofibromatosis patients. We present a female patient with both of these rare types of meningioma. The patient presented with two concurrent intracranial meningiomas, with one a meningotheliomatous subtype and the other a chordoid meningioma. Given the wide array of histological differential diagnoses in chordoid meningioma, immunohistochemistry has a significant role to play in differentiating them. Recurrence in chordoid meningioma can be generally predicted based on the extent of resection, the percentage of chordoid element, and proliferation indices.

摘要

脊索样脑膜瘤根据世界卫生组织(WHO)分类被归类为非典型脑膜瘤,是一种罕见的亚型,仅占所有脑膜瘤的0.5%,且复发率高。在非神经纤维瘤病患者中,多发性颅内脑膜瘤很少见。我们报告了一名患有这两种罕见类型脑膜瘤的女性患者。该患者同时患有两个颅内脑膜瘤,一个是脑膜上皮型亚型,另一个是脊索样脑膜瘤。鉴于脊索样脑膜瘤存在广泛的组织学鉴别诊断,免疫组化在鉴别诊断中具有重要作用。脊索样脑膜瘤的复发通常可根据切除范围、脊索样成分百分比和增殖指数来预测。

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本文引用的文献

1
Chordoid meningioma: a report of ten cases.脊索样脑膜瘤:十例报告。
J Neurooncol. 2010 Aug;99(1):41-8. doi: 10.1007/s11060-009-0097-9. Epub 2010 Jan 22.
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Histological classification and molecular genetics of meningiomas.脑膜瘤的组织学分类与分子遗传学
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