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腹主动脉瘤患者的颈内动脉狭窄共存。

Coexistence of internal carotid artery stenosis in patients with abdominal aortic aneurysm.

机构信息

Clinic for Vascular and Endovascular Surgery, Clinical Centre of Serbia, Belgrade, Serbia.

出版信息

Korean Circ J. 2013 Aug;43(8):550-6. doi: 10.4070/kcj.2013.43.8.550. Epub 2013 Aug 31.

Abstract

BACKGROUND AND OBJECTIVES

Abdominal Aortic Aneurysm (AAA) and carotid disease have medical and social significance, considering their morbidity, disability, and economic consequences. The study objectives were to determine the prevalence of asymptomatic internal carotid artery (ICA) lesions ≥70% in patients with AAA, the correlation of AAA diameter with the degree of ICA stenosis and symptoms, and the importance of preventive ultrasound checkups.

SUBJECTS AND METHODS

A prospective non-randomized controlled study including 740 patients, aged from 18-85 years, who were suitable for the inclusion and exclusion criteria and reported at the vascular laboratory of the Institute for Vascular and Endovascular Surgery, Clinical Center of Serbia from 1st of December 2011 to the 1st of November 2012.

RESULTS

The prevalence of asymptomatic ICA stenosis ≥70% in patients with AAA is 10.8%. Male representatives have more symptomatic ICA stenosis ≥70%. Patients with small aneurysms more often have asymptomatic ICA stenosis ≥70%. The occurrence of symptoms of carotid disease was more prevalent among patients with ICA stenosis ≥70% compared to the group with stenosis <70%. There was no correlation found between the grade of ICA stenosis with the size of AAA.

CONCLUSION

The prevalence of asymptomatic ICA stenosis ≥70% in patients with AAA is found to be 10.8%. Male patients with ICA stenosis ≥70% more often had symptoms of carotid disease. In the smaller aneurysms, ICA stenosis ≥70% occurs frequently, but without the symptoms of carotid disease, and there was no correlation between the size of AAA and the grade of ICA stenosis. Clinical implications of ICA imaging in patients with previously diagnosed AAA is necessary.

摘要

背景与目的

腹主动脉瘤(AAA)和颈动脉疾病具有重要的医学和社会意义,因为它们的发病率、残疾率和经济后果都很高。本研究的目的是确定无症状性颈内动脉(ICA)病变≥70%在 AAA 患者中的患病率,AAA 直径与 ICA 狭窄程度和症状的相关性,以及预防性超声检查的重要性。

对象与方法

这是一项前瞻性、非随机的对照研究,纳入了 2011 年 12 月 1 日至 2012 年 11 月 1 日期间在塞尔维亚临床中心血管和血管外科学研究所血管实验室就诊的符合纳入和排除标准的 740 名年龄在 18-85 岁之间的患者。

结果

AAA 患者无症状性 ICA 狭窄≥70%的患病率为 10.8%。男性患者中更常见有症状性 ICA 狭窄≥70%。小动脉瘤患者更常发生无症状性 ICA 狭窄≥70%。ICA 狭窄≥70%的患者发生颈动脉疾病症状的比例高于狭窄<70%的患者。ICA 狭窄程度与 AAA 大小之间没有相关性。

结论

AAA 患者无症状性 ICA 狭窄≥70%的患病率为 10.8%。ICA 狭窄≥70%的男性患者更常出现颈动脉疾病症状。较小的动脉瘤中,ICA 狭窄≥70%更为常见,但没有颈动脉疾病的症状,AAA 大小与 ICA 狭窄程度之间没有相关性。对已诊断为 AAA 的患者进行 ICA 成像检查具有临床意义。

相似文献

本文引用的文献

1
Should Asian men be included in abdominal aortic aneurysm screening programmes?亚洲男性是否应纳入腹主动脉瘤筛查项目?
Eur J Vasc Endovasc Surg. 2009 Dec;38(6):748-9. doi: 10.1016/j.ejvs.2009.07.012. Epub 2009 Aug 8.
2
Clinical decisions. Management of carotid stenosis.临床决策。颈动脉狭窄的管理
N Engl J Med. 2008 Apr 10;358(15):1617-21. doi: 10.1056/NEJMclde0800741.
6
Occlusion of the internal carotid artery.颈内动脉闭塞。
AMA Arch Neurol Psychiatry. 1951 Mar;65(3):346-77. doi: 10.1001/archneurpsyc.1951.02320030083009.

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