Vision Sciences (R.F., A.T., V.M.), School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, United Kingdom; Department of Optometry (R.F.), King Saud University, Riyadh, Saudi Arabia; and Department of Allied Medical Sciences (M.H.), Jordan University of Science and Technology, Irbid, Jordan.
Eye Contact Lens. 2013 Nov;39(6):365-75. doi: 10.1097/ICL.0b013e318297394c.
To develop with a thin film interferometer new parameters to describe the drying properties of contact lenses; these are: time to first break-up (onset latency), duration of lens surface drying (drying duration), maximum speed of increase in the drying area (maximum speed), and the time to reach maximum drying speed (peak latency). These new parameters were compared with the contact angle (CA) measurement of contact lenses by the captive bubble (CB) technique.
A thin film interferometer was connected to a digital camera, which captured images of the pre-lens liquid film of seven soft contact lenses in vitro: 1-Day Acuvue Moist, ACUVUE Oasys (Johnson & Johnson Vision Care); SofLens 38, PureVision (Bausch & Lomb); AirOptix Night & Day, AirOptix Aqua (CIBA Vision, Corp); and Proclear (Cooper Vision). The images were obtained from the lens surface when it was wet until it became dry (7 images per second) to generate video clips. A program was created in MATLAB to analyze the results. The CAs of the lens surfaces were measured by the CB technique with an OCA-20 contact angle analyzer (Data Physics Instruments).
There were no significant relationships found between the CA and the new drying parameters (P > 0.05). Analysis of the results using analysis of variance and post hoc tests showed that the surface drying dynamics measures effectively differentiated between more of the soft lenses than the CA.
A new technique is described for assessing the drying characteristics of contact lenses by observations of the pattern, size, and speed of pre-lens liquid film break-up observed by a thin film interferometry. The interferometry method allowed evaluation and differentiation between lens materials. This new technique has the major advantage that it can be applied to evaluate contact lens wettability in vivo and in vitro.
利用薄膜干涉仪开发新参数来描述隐形眼镜的干燥特性；这些参数是：首次破裂（起始潜伏期）的时间、镜片表面干燥的持续时间（干燥持续时间）、干燥区域增加的最大速度（最大速度）以及达到最大干燥速度的时间（峰值潜伏期）。这些新参数与通过俘获气泡（CB）技术测量隐形眼镜的接触角（CA）进行了比较。
将薄膜干涉仪连接到数字相机上，该相机捕获了体外的七款软性隐形眼镜的预镜片液体膜的图像：1 日 Acuvue Moist、ACUVUE Oasys（强生视力保健公司）；SofLens 38、PureVision（博士伦）；AirOptix Night & Day、AirOptix Aqua（CIBA Vision，Corp）；和 Proclear（库博光学）。从镜片表面湿润到干燥（每秒 7 张图像）时获得图像，以生成视频剪辑。在 MATLAB 中创建了一个程序来分析结果。使用 OCA-20 接触角分析仪（Data Physics Instruments）通过 CB 技术测量了镜片表面的 CA。
未发现 CA 与新干燥参数之间存在显著关系（P > 0.05）。使用方差分析和事后检验对结果进行分析表明，表面干燥动力学测量有效地将更多软性隐形眼镜与 CA 区分开来。
描述了一种通过观察预镜片液体膜破裂的模式、大小和速度来评估隐形眼镜干燥特性的新技术，该技术采用薄膜干涉仪。干涉仪方法允许评估和区分镜片材料。这种新技术的主要优点是可以应用于评估体内和体外隐形眼镜的润湿性。
