Lansman S L, Ergin M A, Griepp R B
Cardiovasc Clin. 1990;20(2):3-19.
The current success of heart and heart-lung transplantation is grounded in a long progression of experimental and clinical advances. Beginning with an isolated heart transplant performed as a technical exercise in 1905, slowly accumulated experimental efforts yielded solutions to problems involving technique, recipient and graft protection, post-transplant function and immunology, and provided a foundation for subsequent clinical applications. Clinical studies augmented these observations and addressed legal and logistic issues involved in human transplantation.
心脏和心肺移植目前的成功基于一系列漫长的实验和临床进展。始于1905年作为一项技术操作进行的孤立心脏移植，经过逐步积累的实验努力，解决了涉及技术、受体和移植物保护、移植后功能及免疫学等方面的问题，并为后续的临床应用奠定了基础。临床研究进一步丰富了这些观察结果，并解决了人体移植中涉及的法律和后勤问题。
