Cooper David K C
Transplantation Biology Research Center, Department of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.
Tex Heart Inst J. 2004;31(1):61-8.
The experimental investigation of heart transplantation began almost 100 years ago, but it was not until the studies at Stanford Medical School in the late 1950s and early 1960s that clinical transplantation became a realistic possibility. Barnard performed the 1st human-to-human orthotopic heart transplantation in 1967 and followed this by introducing the technique of heterotopic heart transplantation in 1974. Reitz and colleagues at Stanford performed the 1st successful clinical transplantation of the heart and both lungs in 1981. Two years later, at the Toronto General Hospital, successful single-lung transplantation was performed, followed by bilateral lung transplantation in 1986. Aspects of the surgical techniques of these various experimental and clinical procedures are discussed.
心脏移植的实验研究始于近100年前，但直到20世纪50年代末60年代初斯坦福医学院的研究，临床移植才成为一种现实的可能性。1967年，巴纳德进行了首例人与人之间的原位心脏移植，并于1974年引入了异位心脏移植技术。1981年，斯坦福大学的雷茨及其同事进行了首例成功的心脏和双肺临床移植。两年后，在多伦多综合医院进行了成功的单肺移植，随后于1986年进行了双肺移植。本文讨论了这些不同实验和临床手术的外科技术方面。
