Rosenqvist M
Department of Medicine, University of California, San Francisco.
Clin Cardiol. 1990 Jan;13(1):43-7. doi: 10.1002/clc.4960130108.
Atrial pacing is the most physiological way to pace patients with sinus node disease, as it provides both AV synchrony and a normal ventricular activation pattern. Long-term studies comparing atrial and ventricular pacing imply that atrial pacing results in fewer cardiac complications and, possibly, reduced mortality. Ventricular pacing should thus, if possible, be avoided in patients with sinus node disease. The potential risk of impending high-grade AV block during atrial pacing is low, with an annual incidence around 1% if patients are selected appropriately. Approximately 40-50% of patients with sinus node disease show signs of chronotropic incompetence during physical exercise, and are thus candidates for atrial rate responsive pacing. A preoperative evaluation of candidates for atrial pacing should include long-term Holter/telemetry, exercise test, carotid sinus stimulation, and an electrophysiological study excluding significant AV conduction disturbances.
心房起搏是对窦房结疾病患者进行起搏的最生理的方式,因为它能提供房室同步性和正常的心室激动模式。比较心房起搏和心室起搏的长期研究表明,心房起搏导致的心脏并发症更少,并且可能降低死亡率。因此,对于窦房结疾病患者,应尽可能避免心室起搏。如果患者选择得当,心房起搏期间发生高度房室传导阻滞的潜在风险较低,年发生率约为1%。大约40%-50%的窦房结疾病患者在体育锻炼期间表现出变时性功能不全的迹象,因此是心房频率应答性起搏的候选者。对心房起搏候选者的术前评估应包括长期动态心电图/遥测、运动试验、颈动脉窦刺激以及排除显著房室传导障碍的电生理研究。