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Molecular monitoring in NUP214-ABL-positive T-acute lymphoblastic leukemia reveals clonal diversity and helps to guide targeted therapy.

作者信息

Koschmieder S, Burmeister T, Brüggemann M, Berkemeier A, Volpert S, Wieacker P, Silling G, Gökbuget N, Müller-Tidow C, Berdel W E, Stelljes M

机构信息

Department of Medicine A (Hematology and Oncology), University of Münster, Münster, Germany.

Charité, CBF, Med. Klinik für Hämatologie, Onkologie und Tumorimmunologie, Hindenburgdamm 30, Berlin, Germany.

出版信息

Leukemia. 2014 Feb;28(2):419-22. doi: 10.1038/leu.2013.272. Epub 2013 Sep 19.

DOI:10.1038/leu.2013.272
PMID:24048416
Abstract
摘要

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1
Complete morphologic and molecular remission after introduction of dasatinib in the treatment of a pediatric patient with t-cell acute lymphoblastic leukemia and ABL1 amplification.达沙替尼治疗伴有 ABL1 扩增的儿童 T 细胞急性淋巴细胞白血病患者，实现完全形态学和分子学缓解。
Pediatr Blood Cancer. 2012 Aug;59(2):333-4. doi: 10.1002/pbc.23327. Epub 2012 Jan 3.
2
NUP214-ABL1 positive T-cell acute lymphoblastic leukemia patient shows an initial favorable response to imatinib therapy post relapse.NUP214-ABL1阳性T细胞急性淋巴细胞白血病患者复发后对伊马替尼治疗显示出初步良好反应。
Leuk Res. 2011 Jul;35(7):e131-3. doi: 10.1016/j.leukres.2011.03.025. Epub 2011 Apr 13.
3
病例报告：通过下一代测序检测到的急性髓系白血病患者融合基因的首例报告。
Front Oncol. 2021 Jul 8;11:706798. doi: 10.3389/fonc.2021.706798. eCollection 2021.
4
The effect of co-occurring lesions on leukaemogenesis and drug response in T-ALL and ETP-ALL.共患病变对 T-ALL 和 ETP-ALL 白血病发生和药物反应的影响。
Br J Cancer. 2020 Feb;122(4):455-464. doi: 10.1038/s41416-019-0647-7. Epub 2019 Dec 3.
5
Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia.TLX1 和 STAT5 通过协同增强子激活驱动 NUP214-ABL1/TLX1-阳性 T 细胞急性淋巴细胞白血病的发生。
Cancer Cell. 2018 Aug 13;34(2):271-285.e7. doi: 10.1016/j.ccell.2018.07.007.
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Leukemia. 2014 Mar;28(3):543-53. doi: 10.1038/leu.2013.349. Epub 2013 Nov 20.
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Leukemia. 2009 Jan;23(1):125-33. doi: 10.1038/leu.2008.278. Epub 2008 Oct 16.
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NUP214-ABL1 in adult T-ALL: the GMALL study group experience.成人T细胞急性淋巴细胞白血病中的NUP214-ABL1：GMALL研究组的经验
Blood. 2006 Nov 15;108(10):3556-9. doi: 10.1182/blood-2006-04-014514. Epub 2006 Jul 27.
6
Fusion of NUP214 to ABL1 on amplified episomes in T-ALL--implications for treatment.T 细胞急性淋巴细胞白血病中 NUP214 与 ABL1 在扩增附加体上的融合——对治疗的启示
Leukemia. 2005 Sep;19(9):1680-1. doi: 10.1038/sj.leu.2403877.
7
Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia.T细胞急性淋巴细胞白血病中扩增附加体上NUP214与ABL1的融合
Nat Genet. 2004 Oct;36(10):1084-9. doi: 10.1038/ng1425. Epub 2004 Sep 12.
8
Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.白血病残留病检测中融合基因转录本“实时”定量逆转录聚合酶链反应的标准化与质量控制研究——一项欧洲抗癌计划
Leukemia. 2003 Dec;17(12):2318-57. doi: 10.1038/sj.leu.2403135.
9
Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program.利用“实时”定量逆转录聚合酶链反应（RQ-PCR）评估白血病患者诊断及残留疾病检测的候选内参基因——一项欧洲抗癌计划
Leukemia. 2003 Dec;17(12):2474-86. doi: 10.1038/sj.leu.2403136.