Department of Psychiatry, Advanced Centre for Yoga, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
Indian J Psychiatry. 2013 Jul;55(Suppl 3):S374-8. doi: 10.4103/0019-5545.116314.
The efficacy of yoga as an intervention for in-patients with psychosis is as yet unknown; although, previous studies have shown efficacy in stabilized out-patients with schizophrenia.
This study aimed to compare the effect of add-on yoga therapy or physical exercise along with standard pharmacotherapy in the treatment of in-patients with psychosis.
This study was performed in an in-patient setting using a randomized controlled single blind design.
A total of 88 consenting in-patients with psychosis were randomized into yoga therapy group (n=44) and physical exercise group (n=44). Sixty patients completed the study period of 1½ months. Patients who completed in the yoga group (n=35) and in the exercise group (n=25) were similar on the demographic profile, illness parameters and psychopathology scores at baseline.
The two treatment groups were not different on the clinical syndrome scores at the end of 2 weeks. At the end of 6 weeks, patients in the yoga group however had lower mean scores on Clinical Global Impression Severity (CGIS), Positive and Negative Syndrome Scale (total and general psychopathology subscale) and Hamilton Depression Rating Scale (HDRS) (P<0.05). Repeated measure analysis of variance detected an advantage for yoga over exercise in reducing the clinical CGIS and HDRS scores.
Adding yoga intervention to standard pharmacological treatment is feasible and may be beneficial even in the early and acute stage of psychosis.
瑜伽作为一种干预手段在住院精神病患者中的疗效尚不清楚；尽管先前的研究表明在稳定的精神分裂症门诊患者中有效。
本研究旨在比较附加瑜伽疗法或体育锻炼与标准药物治疗对住院精神病患者的治疗效果。
本研究在住院环境中进行，采用随机对照单盲设计。
共有 88 名同意参加的住院精神病患者被随机分为瑜伽治疗组（n=44）和体育锻炼组（n=44）。60 名患者完成了为期 1 个半月的研究期。在瑜伽组（n=35）和锻炼组（n=25）中完成的患者在人口统计学特征、疾病参数和基线时的精神病学评分方面相似。
两组在 2 周结束时的临床综合征评分上没有差异。然而，在 6 周结束时，瑜伽组的患者在临床总体印象严重程度（CGIS）、阳性和阴性综合征量表（总分和一般精神病学分量表）和汉密尔顿抑郁评定量表（HDRS）上的平均评分较低（P<0.05）。重复测量方差分析检测到瑜伽在降低临床 CGIS 和 HDRS 评分方面优于锻炼。
将瑜伽干预措施添加到标准药物治疗中是可行的，即使在精神病的早期和急性期也可能有益。
