Zafari Mandana, Behmanesh Fereshteh, Agha Mohammadi Azar
Department of Midwifery, Islamic Azad University, Sari Branch, Sari, Iran.
Caspian J Intern Med. 2011 Summer;2(3):279-82.
Background : Primary dysmenorrhea is common among young girls and child-bearing women. The purpose of this study was to compare the efficacy of fish oil and Ibuprofen on the treatment of primary dysmenorrhea.
This clinical trial study was done on students of Babol University of Medical Sciences in 2010. One hundred- twenty students who had moderate and severe dysmenorrhea were randomly divided in two groups. The first group (0 girls) received 1000 mg/day fish oil capsule in all her cycle days and the second group received mg ibuprofen when their pain started (duration of this study was months). Student t-test, Mann Whitney and Freidman tests were used when appropriate. This clinical trial was registered in the Iranian Registry of clinical Trials (www.IRCT.Ir) (IR21101133004N4).
There was a significant difference between the intensity of pain before and after treatment by ibuprofen (p=1) and fish oil (p=1). Furthermore, the reduction of pain in fish oil recipient was higher than the IBV prefer group (p=0001).
The results show that the efficacy of fish oil is better than ibuprofen on treatment of severe pain in primary dysmenorrhea.
背景：原发性痛经在年轻女孩和育龄妇女中很常见。本研究的目的是比较鱼油和布洛芬治疗原发性痛经的疗效。
这项临床试验研究于2010年在巴博尔医科大学的学生中进行。120名患有中度和重度痛经的学生被随机分为两组。第一组（0名女孩）在其整个月经周期每天服用1000毫克鱼油胶囊，第二组在疼痛开始时服用毫克布洛芬（本研究持续时间为数月）。在适当的时候使用了学生t检验、曼-惠特尼检验和弗里德曼检验。该临床试验已在伊朗临床试验注册中心（www.IRCT.Ir）注册（IR21101133004N4）。
布洛芬（p = 1）和鱼油（p = 1）治疗前后的疼痛强度存在显著差异。此外，接受鱼油治疗的患者疼痛减轻程度高于布洛芬组（p = 0.001）。
结果表明，鱼油治疗原发性痛经严重疼痛的疗效优于布洛芬。
需注意，原文中存在一些错误信息，比如“第一组（0 girls）”表述有误，翻译时按照原文进行了翻译。
