Kazemi Seyed Ali Naghi, Mousavinasab Nooreddin, Mellati Ali Awsat, Sadeghzadeh Mansour
Zanjan Metabolic Disease Research Center, Pediatric department, Zanjan University of Medical Sciences, Zanjan, Iran.
Int J Prev Med. 2013 Jul;4(7):755-60.
Since cord blood triglyceride level have been reported very different in recent articles, the purpose of this study is determination of triglyceride level in cord blood of Iranian newborns and compare it with other reports.
In this study, cord blood of 174 healthy term newborn infants (97 girls, 77 boys) born from healthy mothers have been used. Triglyceride level has been measured by calorie metric method Statistical analysis was performed by independent t test, Mann-Whitney regression test and Spearman correlation coefficient method using SPSS 16 .0 software (SPSS, USA).
The mean of cord blood triglyceride was 1.37 ± 4.81 mg /dl and there was no statistical difference between two sexes. There was not exist linear relationship between triglyceride and weight, height, head circumference, body mass index and sex of the babies. In 8.6% of our new born infants, triglyceride levels were more than 95th percentile of triglyceride level reported in Iranian population. In 33.9% of our cases, triglyceride levels were more than 95(th) percentile of triglyceride level reported in the Nelson text book of Pediatrics. In this study, the 95th percentile of triglyceride level in cord blood was 132.5 mg /dl.
The mean and 95(th) percentiles of triglyceride levels in cord blood of our newborn infants were higher than other reports. We recommend that larger studies should be conducted in this area to establish preventive ways for increasing epidemic of the metabolic syndrome.
由于近期文章报道的脐血甘油三酯水平差异很大，本研究旨在测定伊朗新生儿脐血中的甘油三酯水平，并与其他报道进行比较。
本研究使用了174名健康足月新生儿（97名女孩，77名男孩）的脐血，这些新生儿均由健康母亲所生。采用比色法测量甘油三酯水平。使用SPSS 16.0软件（美国SPSS公司）进行独立t检验、曼-惠特尼回归检验和斯皮尔曼相关系数法进行统计分析。
脐血甘油三酯的平均值为1.37±4.81mg/dl，两性之间无统计学差异。甘油三酯与婴儿的体重、身高、头围、体重指数和性别之间不存在线性关系。在我们的新生儿中，8.6%的婴儿甘油三酯水平高于伊朗人群报道的甘油三酯水平第95百分位数。在我们33.9%的病例中，甘油三酯水平高于《尼尔森儿科学》教科书中报道的甘油三酯水平第95百分位数。在本研究中，脐血甘油三酯水平的第95百分位数为132.5mg/dl。
我们新生儿脐血甘油三酯水平的平均值和第95百分位数高于其他报道。我们建议在该领域开展更大规模的研究，以建立预防代谢综合征流行增加的方法。
