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新生儿腹部皮下及内脏脂肪厚度:与人体测量学和代谢指标的相关性

Abdominal subcutaneous and visceral fat thickness in newborns: correlation with anthropometric and metabolic profile.

作者信息

Ferreira A P A, da Silva Junior J R, Figueiroa J N, Alves J G B

机构信息

Instituto de Medicina Integral Professor Fernando Figueira (IMIP), Recife, Brazil.

出版信息

J Perinatol. 2014 Dec;34(12):932-5. doi: 10.1038/jp.2014.110. Epub 2014 Jun 5.

DOI:10.1038/jp.2014.110
PMID:24901453
Abstract

OBJECTIVE

To correlate abdominal subcutaneous and visceral fat thickness with anthropometric data and metabolic profile in newborns.

STUDY DESIGN

A cross-sectional study with 99 newborns was performed at Instituto de Medicina Integral Professor Fernando Figueira, Brazil. Abdominal subcutaneous and visceral thickness were measured by ultrasound. Glucose, insulin, homeostatic model assessment-insulin resistance (HOMA-IR), total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, very-low-density lipoprotein cholesterol and triglycerides were determined. Pearson correlation coefficients were calculated.

RESULT

Abdominal subcutaneous fat thickness was positively correlated with birth weight (r=0.31; P<0.001), height (r=0.27; P<0.001) and abdominal circumference (r=0.26; P<0.001), but not with metabolic profile. Abdominal visceral fat thickness was correlated with abdominal circumference (r=0.23; P=0.01), insulin (r=0.21; P=0.04) and HOMA (r=0.24; P=0.02). The results remained the same among males and females.

CONCLUSION

Abdominal fat distribution in newborns has a different correlation with anthropometric and metabolic profile. Abdominal subcutaneous fat thickness is positively correlated with anthropometric data whereas abdominal visceral fat thickness is correlated with insulin and HOMA-IR.

摘要

目的

探讨新生儿腹部皮下脂肪和内脏脂肪厚度与人体测量数据及代谢指标之间的相关性。

研究设计

在巴西费尔南多·菲格雷拉综合医学研究所对99例新生儿进行了一项横断面研究。通过超声测量腹部皮下和内脏脂肪厚度。测定血糖、胰岛素、稳态模型评估胰岛素抵抗(HOMA-IR)、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、极低密度脂蛋白胆固醇和甘油三酯水平。计算Pearson相关系数。

结果

腹部皮下脂肪厚度与出生体重(r=0.31;P<0.001)、身高(r=0.27;P<0.001)和腹围(r=0.26;P<0.001)呈正相关,但与代谢指标无关。腹部内脏脂肪厚度与腹围(r=0.23;P=0.01)、胰岛素(r=0.21;P=0.04)和HOMA(r=0.24;P=0.02)相关。男性和女性的结果相同。

结论

新生儿腹部脂肪分布与人体测量和代谢指标的相关性不同。腹部皮下脂肪厚度与人体测量数据呈正相关,而腹部内脏脂肪厚度与胰岛素和HOMA-IR相关。

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