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细菌性阴道病诱发的反应性关节炎:通过有效治疗进行预防

Reactive arthritis induced by bacterial vaginosis: prevention with an effective treatment.

作者信息

Aminzadeh Zohreh, Fadaeian Afsaneh

机构信息

Professor of Medicine, Shahid Beheshti University of Medical Sciences Consultant ID Physician, Loghman Hakim Hospital, Tehran, Iran.

出版信息

Int J Prev Med. 2013 Jul;4(7):841-4.

Abstract

We report a 42-year-old woman with reactive arthritis induced by bacterial vaginosis who presented with oligoarthritis with an additive form, arthralgia, and enthesitis. She hasn't had a history of diarrhea or dysuria or vaginal secretion, or sexually transmitted infections (STIs). The laboratory tests were normal except for a high erythrocyte sedimentation rate (ESR). Her pelvic examination revealed homogeneous white grey and malodorous vaginal discharge on the vaginal wall and Pap smear and Gram-stained smear of vaginal swab was consistent with bacterial vaginosis. She responded to metronidazole therapy and her six-month follow up hasn't shown recurrence of arthritis. As reactive arthritis (ReA) is a paradigm of a rheumatic disease in which the initiating infectious cause is known, so early use of antimicrobial drugs may prevent the development of musculoskeletal symptoms which are triggered by infections.

摘要

我们报告了一名42岁患有细菌性阴道病诱发的反应性关节炎的女性,她表现为少关节炎(呈叠加型)、关节痛和附着点炎。她既往没有腹泻、排尿困难、阴道分泌物异常或性传播感染(STIs)的病史。除红细胞沉降率(ESR)升高外,实验室检查均正常。她的盆腔检查发现阴道壁有均匀的灰白色且有异味的阴道分泌物,阴道拭子的巴氏涂片和革兰氏染色涂片结果与细菌性阴道病相符。她对甲硝唑治疗有反应,六个月的随访未显示关节炎复发。由于反应性关节炎(ReA)是一种已知起始感染病因的风湿性疾病范例,因此早期使用抗菌药物可能预防由感染引发的肌肉骨骼症状的发展。

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