Nygaard O G, Csángó P A, Jagars G
Dronningensgate Legesenter, Kristiansand S.
Tidsskr Nor Laegeforen. 1991 Mar 10;111(7):845-7.
Bacterial vaginosis is a common disease in outpatient gynaecological practice. Mobiluncus is one of the bacterial species recently described as associated with bacterial vaginosis. In our study, bacterial vaginosis and Mobiluncus sp. morphotype were identified by means of a Gram-stained smear of the vaginal secretions. 40 women with Mobiluncus sp. associated bacterial vaginosis were treated with 500 mg metronidazole three times daily for seven days. 38 (95%) of the 40 patients showed no signs or symptoms of bacterial vaginosis after treatment, and the Mobiluncus sp. morphotype was absent from the Gram-stained smears in all 38 women. At the second control visit one month later, the Gram-stain was normal and no complaints of discharge were noted. The treatment had a favourable effect on the following signs and symptoms of bacterial vaginosis: homogeneous discharge, spotting/postcoital/intermenstrual bleeding, low abdominal pain, pH greater than 4.7. The reduction of these symptoms was statistically significant. The treatment reduced the presence of Mobiluncus, G vaginalis and led to the restoration of Lactobacillus flora. Mobiluncus associated bacterial vaginosis can be treated successfully with 500 mg of metronidazole three times a day for seven days.
细菌性阴道病是妇科门诊常见疾病。动弯杆菌属是最近被描述为与细菌性阴道病相关的细菌种类之一。在我们的研究中，通过阴道分泌物革兰氏染色涂片鉴定细菌性阴道病和动弯杆菌属形态型。40例患有动弯杆菌属相关细菌性阴道病的女性患者接受了每日3次、每次500毫克甲硝唑治疗，疗程7天。40例患者中有38例（95%）治疗后无细菌性阴道病的体征或症状，且这38名女性的革兰氏染色涂片中均未出现动弯杆菌属形态型。在1个月后的第二次复诊时，革兰氏染色正常，未发现有白带异常的主诉。该治疗对细菌性阴道病的以下体征和症状有良好效果：均质白带、点滴状出血/性交后/经间期出血、下腹部疼痛、pH值大于4.7。这些症状的减轻具有统计学意义。该治疗减少了动弯杆菌属、阴道加德纳菌的存在，并使乳酸杆菌菌群得以恢复。动弯杆菌属相关细菌性阴道病每日3次、每次500毫克甲硝唑、疗程7天的治疗方案可成功治愈。
