Mahyari Mojtaba, Shaabani Shabnam, Shaabani Ahmad, Ng Seik Weng
Faculty of Chemistry, Shahid Beheshti University, G. C., P. O. Box 19396-4716, Tehran, Iran.
Comb Chem High Throughput Screen. 2013 Dec;16(10):858-64. doi: 10.2174/13862073113169990051.
A Passerini-type condensation for the synthesis of α-acyloxycarboxamides starting from simple and readily available inputs, including an isocyanide, aldehydes and water in the presence of trimethylsilyl azide as a catalyst under reflux conditions in toluene in good yields, is described.
描述了一种帕瑟里尼型缩合反应，该反应以简单且易于获得的原料（包括异腈、醛和水）为起始物，在三甲基硅叠氮作为催化剂的存在下，于甲苯中回流条件下，以良好的产率合成α-酰氧基羧酰胺。
