Division of Nephrology, West China Hospital of Sichuan University , Chengdu, Sichuan , China.
Ren Fail. 2014 Feb;36(1):108-10. doi: 10.3109/0886022X.2013.832857. Epub 2013 Sep 24.
In recent years, focal segmental glomerulosclerosis has become the commonest cause of the nephrotic syndrome seen in adults. Secondary focal segmental glomerulosclerosis is observed when glomerular workload is increased. We report a case of focal segmental glomerulosclerosis with nephrotic syndrome secondary to high-altitude polycythemia (HAPC). Our case points out that for patients with focal segmental glomerulosclerosis, who presented with nephrotic syndrome secondary to HAPC, treatments for HAPC are crucial for the reduction of proteinuria and renal protection instead of glucocorticoid and immunosuppressive drugs.
近年来,局灶节段性肾小球硬化症已成为成人肾病综合征中最常见的病因。当肾小球工作量增加时,会观察到继发性局灶节段性肾小球硬化症。我们报告了一例继发于高原红细胞增多症(HAPC)的局灶节段性肾小球硬化症合并肾病综合征的病例。我们的病例指出,对于患有局灶节段性肾小球硬化症且因 HAPC 而出现肾病综合征的患者,针对 HAPC 的治疗对于减少蛋白尿和肾脏保护至关重要,而不是糖皮质激素和免疫抑制剂。