Ben-Yehuda-Salz D, Ben-Yehuda A, Polliack A, Ron N, Okon E
Hematology Department, Hadassah University Hospital, Jerusalem, Israel.
Cancer. 1990 Mar 1;65(5):1167-72. doi: 10.1002/1097-0142(19900301)65:5<1167::aid-cncr2820650523>3.0.co;2-v.
The clinicopathologic and histopathologic features of an unusual morphologic variant of nodular sclerosing Hodgkin's Disease (HD) termed the syncytial variant has been reported recently. We report eight new cases with this unique morphology, identified by reviewing the histopathology of 58 patients with nodular sclerosing HD treated in our institute between 1982 and 1988. The clinicopathologic and histopathologic data of these cases are reported and we emphasize this new entity and the difficulties encountered in the morphologic diagnosis. All of the eight patients had a difficult initial clinical course, and were in a clinically advanced stage of the disease at the time of diagnosis. We cite a statistical comparison of the clinical features of the different forms of nodular sclerosing HD.
最近有报道称，结节硬化型霍奇金病（HD）存在一种不寻常的形态学变异型，称为合胞体变异型，其临床病理和组织病理学特征已有相关报道。我们通过回顾1982年至1988年间在我院接受治疗的58例结节硬化型HD患者的组织病理学，确定了8例具有这种独特形态的新病例。报告了这些病例的临床病理和组织病理学数据，并强调了这一新实体以及形态学诊断中遇到的困难。这8例患者均经历了艰难的初始临床病程，诊断时均处于疾病的临床晚期。我们引用了不同形式结节硬化型HD临床特征的统计学比较。
