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关节炎患者样本中与残疾相关的因素。

Factors associated with disability in a sample of adults with arthritis.

机构信息

University of South Carolina, Columbia, SC, USA.

出版信息

Disabil Health J. 2013 Oct;6(4):377-84. doi: 10.1016/j.dhjo.2013.04.008. Epub 2013 Jun 12.

Abstract

BACKGROUND

Arthritis is the most common cause of disability among US adults. Few studies have comprehensively examined factors associated with disability in this population.

OBJECTIVE

To investigate the relationship between a number of disease and non-disease related factors and disability in sample of adults with self-reported doctor-diagnosed arthritis.

METHODS

Participants (n = 396) taking part in a randomized controlled trial of arthritis self-management completed a comprehensive survey assessing a number of demographic, arthritis-specific, health-related, behavioral, and psychological variables at baseline. Disability, as measured by the Health Assessment Questionnaire (HAQ), was also measured. Hierarchical regression models examined the independent associations between blocks of variables and disability.

RESULTS

Demographic variables (R(2) = 0.13), arthritis-specific demographics (i.e., type, medication use; ΔR(2) = 0.16), physical health-related variables (ΔR(2) = 0.06), arthritis-specific symptoms (ΔR(2) = 0.12), health behaviors (ΔR(2) = 0.00), and psychological variables (ΔR(2) = 0.03) explained 50% of the variance in disability score (R(2) = 0.50). With the exception of health behaviors, the addition of each block of variables significantly improved the model, explaining additional variance in HAQ scores (p < 0.0001). In the final model, older age, less than a high school education, rheumatoid arthritis, greater arthritis duration, taking steroids, taking narcotics, greater pain, greater stiffness, greater depressive symptoms, and lower arthritis self-efficacy were associated with greater disability whereas male gender, fibromyalgia, and excellent/very good health were associated with less disability.

CONCLUSIONS

A number of disease and non-disease related variables were associated with disability. These findings suggest that disability in adults with arthritis may be a complicated phenomenon; such complexity may make decreasing disability in this population challenging.

摘要

背景

关节炎是美国成年人中最常见的致残原因。很少有研究全面检查与该人群残疾相关的疾病和非疾病因素。

目的

调查在自我报告的医生诊断为关节炎的成年人群中,许多疾病和非疾病相关因素与残疾之间的关系。

方法

参与关节炎自我管理随机对照试验的参与者(n=396)在基线时完成了一项综合调查,评估了许多人口统计学、关节炎特异性、健康相关、行为和心理变量。残疾(用健康评估问卷(HAQ)衡量)也进行了测量。层次回归模型检查了变量块与残疾之间的独立关联。

结果

人口统计学变量(R²=0.13)、关节炎特异性人口统计学变量(即类型、药物使用;ΔR²=0.16)、身体健康相关变量(ΔR²=0.06)、关节炎特异性症状(ΔR²=0.12)、健康行为(ΔR²=0.00)和心理变量(ΔR²=0.03)解释了残疾评分方差的 50%(R²=0.50)。除了健康行为外,每个变量块的添加都显著改善了模型,解释了 HAQ 评分的额外方差(p<0.0001)。在最终模型中,年龄较大、受教育程度较低、类风湿性关节炎、关节炎持续时间较长、服用类固醇、服用麻醉剂、疼痛较大、僵硬较大、抑郁症状较重、关节炎自我效能较低与残疾程度较大相关,而男性、纤维肌痛和极好/非常好的健康与残疾程度较低相关。

结论

许多疾病和非疾病相关的变量与残疾有关。这些发现表明,关节炎成年人的残疾可能是一种复杂的现象;这种复杂性可能使降低该人群的残疾程度具有挑战性。

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