Heyder N, Günter E, Giedl J, Obenauf A, Hahn E G
Medizinische Klinik I mit Poliklinik, Universität Erlangen-Nürnberg.
Dtsch Med Wochenschr. 1990 Feb 16;115(7):243-7. doi: 10.1055/s-2008-1064999.
Ultrasound examination of the gallbladder was performed in a prospective study (from 1985 to 1988) of 14,841 consecutive patients. Polypoid changes were found in 224 (129 men, 95 women; mean age 54 [18-88] years), sonographically classified as cholesterol polyps in 212, as polypoid lesions of uncertain benignity in 12. Mean observation time of 92 patients with cholesterol polyps was 9 (3-48) months. In six the polyp diameter increased by up to 5 mm: only two of them were operated upon and the diagnosis was confirmed in both. A total of 21 patients suspected of having cholesterol polyps were operated upon, the diagnosis confirmed in 17, chronic cholecystitis in two and, in one case each, thickened wall-adherent bile or wall-adherent concrements as cause of the ultrasound changes. Six of the 12 patients with polypoid lesions of uncertain benignity were operated upon: two had an adenoma, one each had tissue heterotopy, malignant melanoma metastasis, gall-bladder carcinoma and adenomyomatosis.
在一项前瞻性研究(1985年至1988年)中,对14841例连续患者进行了胆囊超声检查。发现224例(129例男性,95例女性;平均年龄54岁[18 - 88岁])有息肉样改变,超声检查分类为胆固醇息肉212例,良性不确定的息肉样病变12例。92例胆固醇息肉患者的平均观察时间为9个月(3 - 48个月)。6例息肉直径增加达5毫米:其中仅2例接受手术,二者均确诊。共有21例疑似胆固醇息肉的患者接受手术,17例确诊,2例为慢性胆囊炎,1例因壁附着胆汁增厚、1例因壁附着结石为超声改变的原因。12例良性不确定的息肉样病变患者中有6例接受手术:2例为腺瘤,各1例为组织异位、恶性黑色素瘤转移、胆囊癌和腺肌增生症。