Chen Ke-neng
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing Cancer Hospital, Peking University, Beijing 100142, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Sep;16(9):811-4.
Esophageal squamous cell carcinoma (ESCC) is one of the commonest malignancies in China. Surgery is the main treatment for ESCC. However, the long-term survival is very poor by surgery alone. Perioperative multimodality treatment, including locally and systemically administrated, preoperatively and postoperatively, has been and will be the standard treatment in terms of improving long-term survival. Base on decades of practice and clinical trials, it is believed that preoperative treatment is better than postoperative treatment, and that chemotherapy plus radiotherapy preoperatively is better than either chemotherapy or radiotherapy alone. Therefore, preoperative radiochemotherapy followed by surgery is the standard treatment and future direction for locally advanced ESCC.
食管鳞状细胞癌（ESCC）是中国最常见的恶性肿瘤之一。手术是ESCC的主要治疗方法。然而，仅靠手术长期生存率非常低。围手术期多模式治疗，包括术前和术后的局部及全身治疗，一直并将继续是提高长期生存率的标准治疗方法。基于数十年的实践和临床试验，人们认为术前治疗优于术后治疗，术前化疗加放疗优于单纯化疗或单纯放疗。因此，术前放化疗后再行手术是局部晚期ESCC的标准治疗方法和未来发展方向。
