Kwek H S, Wilson M, Newman H N
Institute of Dental Surgery, Eastman Dental Hospital, London, UK.
J Clin Periodontol. 1990 Feb;17(2):119-22. doi: 10.1111/j.1600-051x.1990.tb01073.x.
In this study, mycoplasma were enumerated in the gingival crevicular fluid (GCF) of gingivitis and periodontitis patients. GCF samples were obtained from the mesial (approximal) gingival crevice or periodontal pocket of the maxillary right first permanent molar. Samples were cultured anaerobically on a medium selective for mycoplasmas as well as on a non-selective medium to obtain a total anaerobic count. Mycoplasmas were present in the GCF of both gingivitis and periodontitis patients, but a greater % was obtained from the GCF of patients with periodontitis. The proportions of mycoplasma appeared to be independent of the disease activity as expressed by bleeding on probing (PBI), but to be related to probable pocket depth, as shown by the higher %s in periodontitis than gingivitis for a given PBI. On the basis of an increased proportion in relation to disease severity, mycoplasmas would therefore appear to be amongst those micro-organisms associated with CIPD.
在本研究中，对牙龈炎和牙周炎患者的龈沟液（GCF）中的支原体进行了计数。GCF样本取自上颌右侧第一恒磨牙的近中（邻面）龈沟或牙周袋。样本在对支原体有选择性的培养基以及非选择性培养基上进行厌氧培养，以获得总厌氧菌计数。支原体存在于牙龈炎和牙周炎患者的GCF中，但牙周炎患者的GCF中获得的比例更高。支原体的比例似乎与探诊出血（PBI）所表示的疾病活动无关，但与可能的牙周袋深度有关，如在给定PBI时，牙周炎患者的比例高于牙龈炎患者所示。基于与疾病严重程度相关的比例增加，因此支原体似乎是与慢性炎症性牙周病（CIPD）相关的微生物之一。
