Xu Li-Ran, Wang Dong-Xu, Guo Jian-Zhong, Yang Xiao-Ping, Xiu-Xia Ma, Meng Peng-Fei
AIDS Treatment and Research Center, First Affiliated Hospital of Henan College of Traditional Chinese Medicine, Zhengzhou 450000, China.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Jul;33(7):896-900.
To explore Chinese medicine syndrome distribution laws of asymptomatic HIV infection patients.
Using Chi-square test, Chinese medicine syndrome distribution laws were compared and analyzed in 1 156 asymptomatic HIV infection patients from March 2009 to October 2011 from four aspects, i.e., age, possible infection time, disease duration, and different routes of infection.
Qi deficiency syndrome (QDS) and internal dampness-heat accumulation syndrome (IDHAS) were dominant in all syndrome types. Along with aging, QDS showed a growing tendency, while IDHAS showed obvious declining tendency. There was no obvious change in other syndrome types. There was statistical difference in the distribution of each syndrome type among each age period (P < 0.01). Within 15 years, along with the increase of infection time, QDS showed a growing tendency, while IDHAS ratio showed an obvious declining tendency. No obvious laws were found in other syndrome types. There was statistical difference in the distribution of each syndrome type (P < 0.01). Along with the prolongation of disease duration, the case number of each syndrome showed a decreasing trend, but QDS and IDHAS still accounted for higher ratios in each stage. There was statistical difference in the distribution of each syndrome type (P < 0.01). As for infection routes, QDS was predominant in paid blood donation, blood transfusion infection, intravenous drugs. IDHAS was predominant in sexual transmit. No obvious laws were found in other syndrome types. There was statistical difference in the distribution of each syndrome type (P < 0.01).
DIS, IDHAS, and no confirmable syndrome typing were dominant in asymptomatic HIV infection patients. Deficiency and dampness were important pathological factors for them.
探讨无症状HIV感染患者的中医证候分布规律。
采用卡方检验，对2009年3月至2011年10月期间来自四个方面（年龄、可能感染时间、病程和不同感染途径）的1156例无症状HIV感染患者的中医证候分布规律进行比较分析。
在所有证候类型中，气虚证（QDS）和内湿热蕴证（IDHAS）占主导地位。随着年龄增长，QDS呈上升趋势，而IDHAS呈明显下降趋势。其他证候类型无明显变化。各年龄组间各证候类型分布有统计学差异（P<0.01）。15年内，随着感染时间增加，QDS呈上升趋势，而IDHAS比例呈明显下降趋势。其他证候类型未发现明显规律。各证候类型分布有统计学差异（P<0.01）。随着病程延长，各证候病例数呈下降趋势，但QDS和IDHAS在各阶段仍占较高比例。各证候类型分布有统计学差异（P<0.01）。至于感染途径，QDS在有偿献血、输血感染、静脉吸毒中占主导。IDHAS在性传播中占主导。其他证候类型未发现明显规律。各证候类型分布有统计学差异（P<0.01）。
无症状HIV感染患者中，气虚证、内湿热蕴证及未定型占主导。虚证和湿证是其重要病理因素。
