University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, The Netherlands.
Schizophr Res. 2013 Nov;150(2-3):410-5. doi: 10.1016/j.schres.2013.08.037. Epub 2013 Sep 21.
The aim of this study is to describe the psychometric properties of the Antipsychotics and Sexual Functioning Questionnaire (ASFQ). Internal reliability, test-retest reliability, inter-rater reliability, validity and sensitivity to change were calculated in a sample of 30 patients with schizophrenia or a schizophrenia spectrum disorder using antipsychotics. The ASFQ is a semistructured interview, with good face validity and content validity, that takes on average about 10min to complete. The ASFQ has good internal reliability (Cronbach's alpha 0.84) and good test-retest reliability (mean Spearman's rho=.76). The inter-rater reliability is good for questions about libido, orgasm, erection and ejaculation. Correlation coefficients for calculating convergent validity were modest to good when comparing the ASFQ with the corresponding items on the Subject's Response to Antipsychotics (SRA) questionnaire and the Arizona Sexual Experience Scale (ASEX). Based on preliminary evidence, it can be concluded that the Antipsychotics and Sexual Functioning Questionnaire has reasonable reliability and is available for clinical use and research.
本研究旨在描述抗精神病药物与性功能问卷（ASFQ）的心理测量特性。采用抗精神病药物治疗的 30 例精神分裂症或精神分裂症谱系障碍患者的样本中，计算了内部信度、重测信度、评分者间信度、效度和变化敏感性。ASFQ 是一种半结构化访谈，具有良好的表面效度和内容效度，平均完成时间约为 10 分钟。ASFQ 具有良好的内部信度（Cronbach's alpha 0.84）和良好的重测信度（平均 Spearman's rho=.76）。关于性欲、性高潮、勃起和射精的问题，评分者间信度良好。当将 ASFQ 与 Subject's Response to Antipsychotics（SRA）问卷和 Arizona Sexual Experience Scale（ASEX）的相应项目进行比较时，计算收敛效度的相关系数为中等至良好。基于初步证据，可以得出结论，抗精神病药物与性功能问卷具有合理的可靠性，可用于临床使用和研究。
