Shanxi Normal University, Linfen 041004, PR China.
Biosens Bioelectron. 2014 Feb 15;52:271-6. doi: 10.1016/j.bios.2013.08.011. Epub 2013 Aug 30.
Quantum dots (QDs) nanohybrids are an effective route to obtain new property of materials, and are very significant for developing specific materials and improving the performance of existing QDs materials. The objectives of this work are to prepare MPA-capped Mn-doped ZnS QDs/CTAB nanohybrids (MPA: 3-mercaptopropionic acid; CTAB: cetyltrimethyl ammonium bromide) through electrostatic self-assembly, to investigate the formation mechanism and the Room-Temperature Phosphorescenee (RTP) changes, and to explore the possibility of their application in detection of rutin. As a result, MPA-capped Mn-doped ZnS QDs/CTAB nanohybrids greatly improve the rutin detection ability of QDs and provide an important method for developing more convenient and effective rutin detection sensor. The sensor for rutin gave a detection limit of 0.037 mg L(-1) and two linear ranges from 0.05 to 0.5 mg L(-1) and from 0.5 to 5 mg L(-1), and thus can be expanded to selective detection of other substances. Since the present QDs-based RTP method does not need deoxidants or other inducers as conventional RTP detection methods, and avoids interference from autofluorescence and the scattering light of the matrix that are encountered in spectrofluorometry, this method can be used to detect the content of rutin in body fluid.
量子点（QD）纳米杂化材料是获得新材料性能的有效途径，对于开发特定材料和提高现有 QD 材料的性能具有非常重要的意义。本工作的目的是通过静电自组装制备巯基丙酸（MPA）封端的 Mn 掺杂 ZnS QDs/CTAB 纳米杂化材料（MPA：3-巯基丙酸；CTAB：十六烷基三甲基溴化铵），研究其形成机制和室温磷光（RTP）变化，并探讨其在芦丁检测中的应用可能性。结果表明，MPA 封端的 Mn 掺杂 ZnS QDs/CTAB 纳米杂化材料大大提高了 QDs 的芦丁检测能力，为开发更方便、更有效的芦丁检测传感器提供了重要方法。该传感器对芦丁的检测限为 0.037mg/L，线性范围为 0.05-0.5mg/L 和 0.5-5mg/L，因此可以扩展到对其他物质的选择性检测。由于本研究中的基于 QD 的 RTP 方法不需要传统 RTP 检测方法所需的还原剂或其他诱导剂，并且避免了分光光度法中遇到的自荧光和基质散射光的干扰，因此可以用于检测体液中芦丁的含量。
