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[非瓣膜性心房颤动的治疗管理。2013年更新]

[Therapeutic management of non-valvular atrial fibrillation. Update 2013].

作者信息

Bode K, Sommer P, Bollmann A, Hindricks G

机构信息

Abteilung für Rhythmologie, Herzzentrum Leipzig, Universität Leipzig, Strümpellstr. 39, 04289, Leipzig, Deutschland,

出版信息

Herz. 2013 Nov;38(7):743-55; quiz 756-7. doi: 10.1007/s00059-013-3940-x.

Abstract

In western countries one in ten of elderly persons (> 65 years old) will develop atrial fibrillation. The main goal in atrial fibrillation therapy is the prophylaxis of thromboembolic complications through anticoagulation according to the individual risk profile (CHA2DS2-Vasc score) of patients and treatment of cardiovascular comorbidities. Symptoms during atrial fibrillation guide the further therapeutic concept. Doctors can deploy a rate control strategy with a heart rate at rest less than 110/min and/or a rhythm control strategy with cardioversion, antiarrhythmic drugs and catheter ablation to alleviate complaints. To what extent maintaining the sinus rhythm improves the prognosis of atrial fibrillation patients is part of ongoing trials.

摘要

在西方国家,十分之一的老年人(>65岁)会发生房颤。房颤治疗的主要目标是根据患者的个体风险状况(CHA2DS2-Vasc评分)进行抗凝,以预防血栓栓塞并发症,并治疗心血管合并症。房颤期间的症状指导进一步的治疗理念。医生可以采用静息心率低于110次/分钟的心率控制策略和/或采用心脏复律、抗心律失常药物及导管消融的节律控制策略来缓解症状。维持窦性心律在多大程度上能改善房颤患者的预后是正在进行的试验的一部分。

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