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使用傅里叶变换红外显微光谱技术对多能和多潜能干细胞进行特征描述。

The characterisation of pluripotent and multipotent stem cells using Fourier transform infrared microspectroscopy.

机构信息

Department of Anatomy and Developmental Biology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Wellington Road, Clayton, Victoria 3800, Australia.

出版信息

Int J Mol Sci. 2013 Aug 26;14(9):17453-76. doi: 10.3390/ijms140917453.

DOI:10.3390/ijms140917453
PMID:24065090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3794735/
Abstract

Fourier transform infrared (FTIR) microspectroscopy shows potential as a benign, objective and rapid tool to screen pluripotent and multipotent stem cells for clinical use. It offers a new experimental approach that provides a holistic measurement of macromolecular composition such that a signature representing the internal cellular phenotype is obtained. The use of this technique therefore contributes information that is complementary to that acquired by conventional genetic and immunohistochemical methods.

摘要

傅里叶变换红外(FTIR)微光谱分析显示出作为一种良性、客观和快速的工具来筛选多能和多能干细胞用于临床应用的潜力。它提供了一种新的实验方法,对大分子组成进行整体测量,从而获得代表细胞内表型的特征。因此,该技术的使用提供了与传统遗传和免疫组织化学方法获得的信息互补的信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac01/3794735/e75038f16409/ijms-14-17453f8.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac01/3794735/e75038f16409/ijms-14-17453f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac01/3794735/20e7400882aa/ijms-14-17453f1.jpg
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