Department of Neurology, University of Rostock, Gehlsheimer Strasse 20, D-18147 Rostock, Germany. E-email:
J Ultrasound Med. 2013 Oct;32(10):1837-43. doi: 10.7863/ultra.32.10.1837.
The detection of an enlarged echogenic size ("hyperechogenicity") of the substantia nigra on transcranial sonography is increasingly used for the early and differential diagnosis of Parkinson disease. However, the diagnostic value of substantia nigra sonography depends on the quality of its execution. This article with an accompanying video presents a step-by-step description and demonstration of ultrasound system settings, typical errors in assessment of the substantia nigra, planimetric measurement of substantia nigra echogenicity according to current guidelines, and its diagnostic implications in 2 exemplary patients with parkinsonism. Published cutoff values for grading substantia nigra hyperechogenicity with different ultrasound systems and novel technologies are reviewed.
经颅超声检查发现黑质回声增大（“高回声”）越来越多地用于帕金森病的早期和鉴别诊断。然而，黑质超声检查的诊断价值取决于其执行质量。本文附有视频，介绍了超声系统设置的逐步描述和演示、黑质评估中的典型错误、根据当前指南对黑质回声进行的平面测量，以及在 2 例帕金森病患者中的诊断意义。本文还回顾了不同超声系统和新技术分级黑质高回声的发表界值。
