Whipp B J, Ward S A
Department of Physiology, UCLA School of Medicine 90024.
Med Sci Sports Exerc. 1990 Feb;22(1):62-71.
We consider how the optimal selection of the profile of imposed work rate, coupled with rigorous, statistically justified analysis of the pattern of the pulmonary gas exchange response, makes it possible to assemble a control model incorporating the proportional role of the muscle, circulation, and gas stores. Gains, time constants, and delays may be assigned to the components of the response and its linearity assessed. These techniques also allow the investigator to examine the features of poorly understood and even unexpected response patterns. Recent interest in the analysis of the non-steady state of exercise-in normal subjects and in patients with gas exchange defects-has led to an improved understanding of the sub-threshold dynamics. At work rates above the lactate threshold, the more complex kinetics are to date poorly described, and hence poorly understood, remaining a fertile area for the application of control-systems techniques to exercise.
我们探讨了如何通过优化设定工作率的曲线，并结合对肺气体交换反应模式进行严格的、具有统计学依据的分析，来构建一个包含肌肉、循环和气体储备比例作用的控制模型。可以为反应的各个组成部分赋予增益、时间常数和延迟，并评估其线性度。这些技术还使研究人员能够研究理解不足甚至意想不到的反应模式的特征。最近对正常受试者和有气体交换缺陷患者运动非稳态分析的关注，增进了我们对阈下动力学的理解。在高于乳酸阈的工作率下，迄今为止对更复杂的动力学描述甚少，因此理解也不足，这仍然是控制系统技术应用于运动研究的一个富有成果的领域。
