Goossens N, Negro F
Service de gastroentérologie et hépatologie, Département des spécialités de médecine, HUG, 1211 Genève 14.
Rev Med Suisse. 2013 Sep 4;9(396):1566, 1568-71.
The hepatitis B virus is an important cause of viral reactivation and flares in immunosuppressed patients. Factors associated with viral reactivation include positive HBs antigen, rituximab treatment, onco-haematological pathology and bone marrow transplantation. In situations at high risk of viral reactivation prophylactic antiviral therapy is indicated and reduces morbidity and mortality related to viral hepatitis flares.