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教育项目可提高慢性肾脏病患者的透析准备和生存状况。

Educational programs improve the preparation for dialysis and survival of patients with chronic kidney disease.

机构信息

1] VA Palo Alto Health Care System, Geriatrics Research Education and Clinical Center, Palo Alto, California, USA [2] Division of Nephrology, Stanford University School of Medicine, Palo Alto, California, USA.

Chronic Disease Research Group, Minneapolis Medical Research Foundation, Minneapolis, Minneapolis, USA.

出版信息

Kidney Int. 2014 Mar;85(3):686-92. doi: 10.1038/ki.2013.369. Epub 2013 Sep 25.

Abstract

Preparation for end-stage renal disease (ESRD) is widely acknowledged to be suboptimal in the United States. We sought to determine whether participation in a kidney disease screening and education program resulted in improved ESRD preparation and survival in 595 adults who developed ESRD after participating in the National Kidney Foundation Kidney Early Evaluation Program (KEEP), a community-based screening and education program. Non-KEEP patients were selected from a national ESRD registry and matched to KEEP participants based on demographic and clinical characteristics. The main outcomes were pre-ESRD nephrologist care, placement of permanent vascular access, use of peritoneal dialysis, pre-emptive transplant wait listing, transplantation, and mortality after ESRD. Participation in KEEP was associated with significantly higher rates of pre-ESRD nephrologist care (76.0% vs. 69.3%), peritoneal dialysis (10.3% vs. 6.4%), pre-emptive transplant wait listing (24.2% vs. 17.1%), and transplantation (9.7% vs. 6.4%) but not with higher rates of permanent vascular access (23.4% vs. 20.1%). Participation in KEEP was associated with a lower risk for mortality (hazard ratio 0.80), but this was not statistically significant after adjusting for ESRD preparation. Thus, participation in a voluntary community kidney disease screening and education program was associated with higher rates of ESRD preparation and survival.

摘要

美国普遍认为终末期肾病 (ESRD) 的准备工作并不理想。我们旨在确定参与肾脏病筛查和教育计划是否会改善在参与基于社区的筛查和教育计划——国家肾脏基金会肾脏病早期评估计划 (KEEP) 后发生 ESRD 的 595 名成年人的 ESRD 准备和生存。非 KEEP 患者从全国 ESRD 登记处选择,并根据人口统计学和临床特征与 KEEP 参与者匹配。主要结果是 ESRD 前肾病学家的护理、永久性血管通路的放置、腹膜透析的使用、抢先移植等待名单、移植以及 ESRD 后的死亡率。参与 KEEP 与更高的 ESRD 前肾病学家护理率(76.0%对 69.3%)、腹膜透析率(10.3%对 6.4%)、抢先移植等待名单率(24.2%对 17.1%)和移植率(9.7%对 6.4%)相关,但与永久性血管通路率(23.4%对 20.1%)无关。参与 KEEP 与死亡率降低相关(风险比 0.80),但在调整 ESRD 准备后,这并不具有统计学意义。因此,参与自愿社区肾脏病筛查和教育计划与更高的 ESRD 准备和生存相关。

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