致命性肺炎患者中金黄色葡萄球菌与流感病毒合并感染的分子特征
Molecular characterization of Staphylococcus aureus and influenza virus coinfections in patients with fatal Pneumonia.
作者信息
Denison Amy M, Deleon-Carnes Marlene, Blau Dianna M, Shattuck Eric C, McDougal Linda K, Rasheed James K, Limbago Brandi M, Zaki Sherif R, Paddock Christopher D
机构信息
Division of High-Consequence Pathogens and Pathology.
出版信息
J Clin Microbiol. 2013 Dec;51(12):4223-5. doi: 10.1128/JCM.02503-13. Epub 2013 Sep 25.
Abstract
Molecular techniques were used to characterize genetic features of Staphylococcus aureus in 66 fatal cases of pneumonia caused by S. aureus and influenza A or B viruses. Nucleic acids were extracted from formalin-fixed, paraffin-embedded tissues. The majority of cases revealed genetic markers for Panton-Valentine leukocidin, mecA, and spa type t008.
摘要
采用分子技术对66例由金黄色葡萄球菌及甲型或乙型流感病毒引起的致命性肺炎病例中金黄色葡萄球菌的基因特征进行了鉴定。从福尔马林固定、石蜡包埋组织中提取核酸。大多数病例显示出杀白细胞素、mecA和spa t008型的基因标记。
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