Cuilleret J, Guillemin G
Chirurgien des Hopitaux, Service de Chirurgie Digestive C.H.U. de Saint-Etienne, France.
World J Surg. 1990 Jan-Feb;14(1):11-8. doi: 10.1007/BF01670539.
Surgical management of chronic pancreatitis remains a difficult problem. On the continent of Europe, the main etiology of the disease is alcoholism; thus, alcohol withdrawal is mandatory before surgical treatment. Left splanchnicectomy is no longer used. Total and left subtotal pancreatectomy are abandoned due to their high mortality rates and their severe metabolic sequelae. Distal pancreatectomy is presently reserved for the cases in which the head of the pancreas is least involved. The choice between pancreaticojejunostomy and pancreaticoduodenectomy remains debated. The former has a low postoperative mortality rate while reoperation is less frequent after the latter. Current trends in Europe are to perform more anastomoses and less resections than some years ago. Pancreaticoduodenectomy, however, retains an important role in cases with biliary or duodenal involvement. Whatever the choice of the procedure, the surgical treatment of chronic pancreatitis remains palliative and does not alter the natural course of the disease. The quality and duration of the results depend mainly on alcohol withdrawal.
慢性胰腺炎的外科治疗仍然是一个难题。在欧洲大陆,该病的主要病因是酗酒;因此,手术治疗前必须戒酒。左侧内脏神经切除术已不再使用。全胰切除术和左半胰切除术因其高死亡率和严重的代谢后遗症而被摒弃。目前,远端胰腺切除术仅适用于胰腺头部受累最轻的病例。胰空肠吻合术和胰十二指肠切除术之间的选择仍存在争议。前者术后死亡率低,而后者再次手术的频率较低。与几年前相比,欧洲目前的趋势是进行更多的吻合术和更少的切除术。然而,胰十二指肠切除术在伴有胆管或十二指肠受累的病例中仍起着重要作用。无论选择何种手术方式,慢性胰腺炎的外科治疗仍然是姑息性的,并且不会改变疾病的自然病程。治疗效果的质量和持续时间主要取决于戒酒情况。