Burns Unit, Reconstructive Sciences Department, Hospital Universiti Sains Malaysia, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kota Bharu, Kelantan, Malaysia.
Burns. 2010 Sep;36(6):897-904. doi: 10.1016/j.burns.2009.03.007. Epub 2010 Mar 17.
Glycerol-preserved skin allograft (GPA) plays a crucial role in the management of burns. Its indications include wound-bed preparation, definitive dressing and sandwich grafting technique.
We analysed the experience of using GPA and its efficacy in burn treatment in our burn centre.
All burns managed with GPA in our burn centre from October 2001 to May 2008 were analysed.
Mean total body surface area (TBSA) of 43 consecutive cases was 28.7%. GPA adhered to the wound for an average of 8.4 days before rejection. The length of hospital stay of the survivors was 42.5 days. The autograft take after wound-bed preparation with GPA was 88.4%. For sandwich grafting technique, the autograft take was 74.4%. When GPA was applied for partial-thickness burn as definitive dressing, all patients achieved complete healing within an average of 19 days without further surgical intervention. Despite colonisation of burn wounds after application of skin allograft, the outcomes of autograft take and wound healing were not significantly different.
The selective and strategic use of the GPA in major burn patients ensures optimal benefits in the management of burns. It is versatile in various categories of burn wounds with minimal morbidity.
甘油保存皮肤移植物（GPA）在烧伤治疗中起着至关重要的作用。其适应证包括创面准备、确定性敷料和三明治植皮技术。
我们分析了 GPA 在我们烧伤中心治疗烧伤的经验及其疗效。
分析 2001 年 10 月至 2008 年 5 月期间在我们烧伤中心使用 GPA 治疗的所有烧伤患者。
43 例连续病例的平均总体表面积（TBSA）为 43%。GPA 在被排斥之前平均黏附在伤口上 8.4 天。幸存者的住院时间为 42.5 天。用 GPA 进行创面准备后的自体皮移植成活率为 88.4%。对于三明治植皮技术，自体皮移植成活率为 74.4%。当 GPA 作为确定性敷料用于部分厚度烧伤时，所有患者在无需进一步手术干预的情况下，平均在 19 天内实现完全愈合。尽管在应用皮肤移植物后烧伤创面发生了定植，但自体皮移植成活率和伤口愈合的结果并无显著差异。
在大面积烧伤患者中选择性和策略性地使用 GPA，可确保在烧伤管理中获得最佳效果。它在各种类型的烧伤创面中具有广泛的适用性，且并发症少。
