Telomere biology and translational research.
作者信息
Mason Philip J, Perdigones Nieves
机构信息
Division of Hematology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA.
出版信息
Transl Res. 2013 Dec;162(6):333-42. doi: 10.1016/j.trsl.2013.08.009. Epub 2013 Sep 23.
Abstract
摘要
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Telomere biology and translational research.端粒生物学与转化研究。
Transl Res. 2013 Dec;162(6):333-42. doi: 10.1016/j.trsl.2013.08.009. Epub 2013 Sep 23.
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Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis.平衡不稳定性：端粒酶和端粒功能障碍在肿瘤发生中的双重作用
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Telomerase inhibition and telomere erosion: a two-pronged strategy in cancer therapy.端粒酶抑制与端粒侵蚀：癌症治疗的双管齐下策略。
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Telomere Maintenance Mechanisms in Cancer.癌症中的端粒维持机制
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本文引用的文献
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Biology of telomeres: importance in etiology of esophageal cancer and as therapeutic target.端粒生物学：在食管癌病因学和治疗靶点中的重要性。
Transl Res. 2013 Dec;162(6):364-70. doi: 10.1016/j.trsl.2013.09.003. Epub 2013 Oct 1.
2
High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.肝细胞癌和癌前病变中端粒酶逆转录酶启动子体细胞突变的高频。
Nat Commun. 2013;4:2218. doi: 10.1038/ncomms3218.
3
Frequency of TERT promoter mutations in human cancers.TERT 启动子突变在人类癌症中的频率。
Nat Commun. 2013;4:2185. doi: 10.1038/ncomms3185.
4
Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy.端粒功能障碍在杜氏肌营养不良性心力衰竭中的作用。
Nat Cell Biol. 2013 Aug;15(8):895-904. doi: 10.1038/ncb2790. Epub 2013 Jul 7.
5
Environmental and occupational exposure to chemicals and telomere length in human studies.环境和职业接触化学物质与人类端粒长度。
Occup Environ Med. 2013 Oct;70(10):743-9. doi: 10.1136/oemed-2012-101350. Epub 2013 Jun 17.
6
Telomeres and cardiovascular disease risk: an update 2013.端粒与心血管疾病风险：2013 年最新研究进展
Transl Res. 2013 Dec;162(6):371-80. doi: 10.1016/j.trsl.2013.05.004. Epub 2013 Jun 7.
7
Short telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancy.短端粒：从先天性角化不良到特发性再生障碍性贫血和恶性肿瘤。
Transl Res. 2013 Dec;162(6):353-63. doi: 10.1016/j.trsl.2013.05.003. Epub 2013 Jun 1.
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Stress and telomere biology: a lifespan perspective.压力与端粒生物学：寿命视角。
Psychoneuroendocrinology. 2013 Sep;38(9):1835-42. doi: 10.1016/j.psyneuen.2013.03.010. Epub 2013 Apr 29.
9
Telomeres in lung disease.肺疾病中的端粒
Transl Res. 2013 Dec;162(6):343-52. doi: 10.1016/j.trsl.2013.04.001. Epub 2013 Apr 22.
10
Targeting homologous recombination and telomerase in Barrett's adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth.靶向 Barrett 腺癌中的同源重组和端粒酶：对端粒维持、基因组不稳定性和肿瘤生长的影响。
Oncogene. 2014 Mar 20;33(12):1495-505. doi: 10.1038/onc.2013.103. Epub 2013 Apr 22.
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