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Aminothiadiazole (NSC 4728) in patients with advanced carcinoma of the endometrium. A phase II study of the Gynecologic Oncology group.

作者信息

Asbury R F, Blessing J A, McGuire W P, Hanjani P, Mortel R

机构信息

University of Rochester School of Medicine, NY.

出版信息

Am J Clin Oncol. 1990 Feb;13(1):39-41. doi: 10.1097/00000421-199002000-00011.

Abstract

Twenty-one evaluable patients with advanced carcinoma of the endometrium were treated with aminothiadiazole at a dosage of 125 mg/m2 weekly. Twelve had received prior chemotherapy. Seven patients had stable disease; 14 had increasing disease. There were two life-threatening toxic episodes. Aminothiadiazole used in this dosage and schedule has negligible activity in previously treated patients with carcinoma of the endometrium.

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